1380345-03-8

Basic information

• Product Name: 3-methylsulfinyl-6-phenyl-1,2,4-triazine
• Synonyms: 3-methylsulfinyl-6-phenyl-1,2,4-triazine
• CAS NO: 1380345-03-8
• Molecular Weight: 219.267
• Mol File: 1380345-03-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methylsulfinyl-6-phenyl-1,2,4-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylsulfinyl-6-phenyl-1,2,4-triazine(1380345-03-8)
• EPA Substance Registry System: 3-methylsulfinyl-6-phenyl-1,2,4-triazine(1380345-03-8)

Safety Data

• Hazardous Substances Data: 1380345-03-8(Hazardous Substances Data)

Upstream product

• 1074-12-0 phenylglyoxal hydrate 
• 98-86-2 acetophenone 
• 27623-10-5 3-(methylsulfanyl)-6-phenyl-1,2,4-triazine 
• 6175-45-7 2,2-diethoxyacetophenone 

Downstream Products

• 73214-25-2 3-hydrazino-6-phenyl-1,2,4-triazine 
• 1380344-32-0 6-((6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline 

Relevant articles and documents

[1,2,4]TRIAZOLO[4,3-B][1,2,4]TRIAZINE COMPOUND, PREPARATION METHOD AND USE THEREOF

The present invention relates to a structurally novel [1,2,4]triazolo[4,3-b][1,2,4]triazine compounds represented by formula (I) or formula (II), pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates or solvates thereof, and also relates to a preparation method of the compounds, a pharmaceutical composition comprising a therapeutically effective amount of the compounds, as well as the use thereof as protein tyrosine kinase inhibitors, particularly as c-Met inhibitors, in the preparation of medicaments for the prevention and/or treatment of diseases associated with c-Met abnormality.