1380395-15-2

Basic information

• Product Name: N-benzyl-4-methyl-2-(phenylethynyl)phenylamine
• Synonyms: N-benzyl-4-methyl-2-(phenylethynyl)phenylamine
• CAS NO: 1380395-15-2
• Molecular Weight: 297.4
• Mol File: 1380395-15-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-benzyl-4-methyl-2-(phenylethynyl)phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4-methyl-2-(phenylethynyl)phenylamine(1380395-15-2)
• EPA Substance Registry System: N-benzyl-4-methyl-2-(phenylethynyl)phenylamine(1380395-15-2)

Safety Data

• Hazardous Substances Data: 1380395-15-2(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 13141-44-1 4-methyl-2-(phenylethynyl)aniline 
• 100-52-7 benzaldehyde 
• 29289-13-2 2-iodo-4-methylaniline 

Downstream Products

• 1380395-25-4 methyl 1-benzyl-5-methyl-2-phenyl-1H-indole-3-carboxylate 
• 1380395-36-7 ethyl 1-benzyl-5-methyl-2-phenyl-1H-indole-3-carboxylate 

Relevant articles and documents

Nickel-Catalyzed Arylative Additions on 2-Alkynyl-N-Arylsulfonylanilides to Construct Functionalized Indoles

The addition of aryl iodides to 2-alkynyl-N-sulfonylanilides to form 2,3-difunctionalized N-arylsulfonylindoles can be catalyzed using a nickel catalyst ligated to a bis(cyclohexanyl)phosphinoferrocene. A variety of nickel complexes can be used as precata

Bis(dibenzylideneacetone)palladium(0)/tert-Butyl Nitrite- Catalyzed Cyclization of o-Alkynylanilines with tert-Butyl Nitrite: Synthesis and Applications of Indazole 2-Oxides

An efficient method for the synthesis of 1-benzyl/arylindazole 2-oxides via a bis(dibenzylideneacetone)palladium(0) [Pd(dba)2]/tert-butyl nitrite (TBN)-catalyzed reaction of o-alkynylaniline derivatives with TBN is reported. The overall transfo

A general synthesis of indole-3-carboxylic esters by palladium-catalyzed direct oxidative carbonylation of 2-alkynylaniline derivatives

A general synthesis of indole-3-carboxylic esters by direct Pd-catalyzed oxidative carbonylation of readily available 2-alkynylaniline derivatives is reported. In particular, 2-alkynylanilines bearing an internal triple bond and a secondary amino group (1) were directly converted into indole-3-carboxylic esters 2 in fair to good yields (50-84%) when let to react with CO, O 2, and an alcohol in the presence of the PdI2/ KI catalytic system, under relatively mild conditions [100 °C and 20 atm (at 25 °C) of a 4:1 mixture CO/air]. On the other hand, under similar conditions, but in the presence of HC(OMe)3, 2-alkynylanilines bearing an internal triple bond and a primary amino group (7) afforded 1-(dimethoxymethyl) indole-3-carboxylic esters 9 through the intermediate formation of N-(dimethoxymethyl)-2-alkynylaniline derivatives II. Compounds 9 could be conveniently converted into Nunsubstituted indole-3-carboxylic esters 10 by a simple acidic treatment carried out in MeOH/H2O at 80 °C.