138056-20-9Relevant articles and documents
2-Hydroxyalkyl Diphenylphosphines: Biocatalytic Resolution and Use as Ligands for Transition-metal Catalysts
Kagan, Henri B.,Tahar, Maurice,Fiaud, Jean-Claude
, p. 5959 - 5962 (2007/10/02)
Kinetic resolution of 2-hydroxyalkyldiphenylphosphines 1 by acylation with isopropenyl acetate was carried out under rabbit gastric lipase (RGL) catalysis to give optically active 1 and the corresponding acetate, the enantioselectivity factors E ranging from 10 to 20. Key words: 2-hydroxyalkyldiphenylphosphines; rabbit gastric lipase; kinetic resolution; biocatalysis; acylation