1380599-57-4

Basic information

• Product Name: C₂₃H₁₈O₄
• Synonyms: C₂₃H₁₈O₄
• CAS NO: 1380599-57-4
• Molecular Weight: 358.394
• Mol File: 1380599-57-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₃H₁₈O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₁₈O₄(1380599-57-4)
• EPA Substance Registry System: C₂₃H₁₈O₄(1380599-57-4)

Safety Data

• Hazardous Substances Data: 1380599-57-4(Hazardous Substances Data)

Upstream product

• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 51069-81-9 6-bromo-4-chloro-2H-chromen-2-one 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 638191-63-6 6-bromo-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 4139-61-1 6-bromo-4-hydroxycoumarin 

Relevant articles and documents

Pd-catalyzed chemo-selective mono-arylations and bis-arylations of functionalized 4-chlorocoumarins with triarylbismuths as threefold arylating reagents

Cross-coupling reactions of differently substituted 4-chlorocoumarins were studied under palladium catalysis using triarylbismuths as threefold arylating reagents. The high reactivity of 4-chlorocoumarins was demonstrated delivering mono- and bis-arylation products in a chemo-selective manner. The reaction conditions employed are simple, robust and the threefold coupling reactivity of triarylbismuth reagents was witnessed with good to high yields in 2-4 h conditions. The utility of the methodology was explored in the synthesis of a few natural occurring neoflavones (3.27-3.30). In addition, the 4-arylcoumarin 3.1 product is a useful precursor for the preparation of (R)-tolterodine.