1380650-61-2

Upstream product

• 31603-77-7 4-biphenylacetonitrile 
• 92855-14-6 1-(biphenyl-4-yl)cyclopropanecarbonitrile 
• 1380650-55-4 ethyl 1-(4-phenylphenyl)cyclopropanecarboxylate 
• 1380650-56-5 1-(4'-acetylbiphenyl-4-yl)cyclopropanecarboxylic acid ethyl ester 
• 1380650-58-7 4'-(1-(ethoxycarbonyl)cyclopropyl)biphenyl-4-carboxylic acid 
• 864851-43-4 C₁₁H₁₃NO₂ 
• 61312-70-7 3-methylamino-but-2-enoic acid benzyl ester 

Downstream Products

• 1380650-62-3 benzyl 5-(4'-(1-(ethoxycarbonyl)cyclopropyl)biphenyl-4-yl)-3-methylisoxazole-4-carboxylate 
• 1257213-50-5 (R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid 
• 1257214-10-0 5-(4'-(1-(ethoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-3-methylisoxazole-4-carboxylic acid 
• 1380650-63-4 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester 
• 1380650-53-2 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid sodium salt 

Relevant academic research and scientific papers

POLYCYCLIC LPA1 ANTAGONIST AND USES THEREOF

Described herein is the LPA1 antagonist 1- {4'-[3-methyl-4-((R)- l-phenyl-ethoxycarbonylamino)- isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid (Compound 1), or pharmaceutically acceptable salts thereof. Also described are methods of preparing t

POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.