1380678-75-0Relevant academic research and scientific papers
Palladium-catalyzed alkenylation and alkynylation of ortho-C(sp 2)-H bonds of benzylamine picolinamides
Zhao, Yingsheng,He, Gang,Nack, William A.,Chen, Gong
supporting information; experimental part, p. 2948 - 2951 (2012/08/07)
An efficient functionalization of ortho-C(sp2)-H bonds of picolinamide (PA)-protected benzylamine substrates with a range of vinyl iodides as well as acetylenic bromide is reported. ortho-Phenyl benzoic acid (oPBA) acts as an effective promoter in this reaction system. This method provides a practical strategy to access highly functionalized benzylamine compounds for organic synthesis.
