138112-79-5Relevant articles and documents
Synthesis of naphthalenic melatonin receptor ligands
Chu,Li
, p. 621 - 629 (2007/10/03)
A highly efficient and versatile synthetic approach to the synthesis of naphthalenic analogs of melatonin, compound 7, and its 2-alkyl substituted analog 8 is described. This approach features the novel synthesis of substituted 1-naphthyl acetonitrile 12 and 19 by nucleophilic addition of LiCH2CN to substituted 1-tetralone, followed by aromatization via a 2-step reaction sequence, dehydrogenation with DDQ and TsOH catalyzed dehydration.
Compounds having a naphthalene structure
-
, (2008/06/13)
Compounds of general formula: STR1 in which A and R are defined in the description.