138147-85-0Relevant academic research and scientific papers
Controlled Synthesis of β-Keto Sulfones and Vinyl Sulfones under Electrochemical Oxidation
Fang, Yang,Xu, Dongping,Yu, Yingliang,Tang, Rumeng,Dai, Shuaishuai,Wang, Zhenghua,Zhang, Wu
, (2022/04/09)
Selective sulfonylation and oxosulfonylation of alkenes with sulfinates have been developed via anodic oxidation in an undivided cell. The novel electrosynthetic method provided β-keto sulfones and vinyl sulfones with good to excellent yields in the absence of any transition metal catalyst and oxidants. Mechanism studies show that two different pathways involved in these two transformations.
Copper-Catalyzed Heck-Type Couplings of Sulfonyl Chlorides with Olefins: Efficient and Rapid Access to Vinyl Sulfones
Chen, Qiulin,Liu, Lixia,Wang, Chengming,Xue, Pan
supporting information, (2021/08/27)
A copper-catalyzed redox-neutral alkene sulfonylation reaction has been developed. This reported protocol can be easily scale up to a gram scale, and smoothly applied to the late-stage modification of several bioactive molecules.
Aerobic Copper-Catalyzed Synthesis of (E)-Vinyl Sulfones by Direct C-S Bond Oxidative Coupling
Liang, Xiao,Xiong, Mingteng,Zhu, Heping,Shen, Kexin,Pan, Yuanjiang
, p. 11210 - 11218 (2019/09/12)
Copper-catalyzed aerobic oxidative C-S bond coupling reaction between thiophenols and aryl-substituted alkenes for (E)-vinyl sulfones synthesis is reported here. With air utilized as a green oxidant, this transformation not only produces various vinyl sulfones in moderate to good yields but also possesses a simple and ecofriendly system. To clarify the mechanism, kinetic experiments has been investigated.
Metal-free catalyzed synthesis of the (E)-vinyl sulfones via aromatic olefins with arylsulfonyl hydrazides
Zhan, Zhenzhen,Ma, Haojie,Wei, Daidong,Pu, Jinghong,Zhang, Yixin,Huang, Guosheng
supporting information, p. 1446 - 1450 (2018/03/07)
Synthesis of vinyl sulfones from aromatic olefins and arylsulfonyl hydrazides via I2-TBHP catalyzed system under the N2 atmosphere is described. Owing to no use of metal, only producing N2 and water as the byproducts and d
Preparation method of (E)-alkenyl sulfone compounds
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Paragraph 0011, (2019/01/14)
The invention discloses a preparation method of (E)-alkenyl sulfone compounds. The method comprises the following steps: MeCN-H2O (3:1) is taken as a solvent, I2 and 30% H2O2 oxidize ketone or aldehyde (IV) in presence of p-TsOH, geminal diol peroxide compounds shown in formula (V) are generated in situ, the compounds in formula (V) taken as a peroxidation reagent and I2 are subjected to concertedcatalysis of a reaction between aryl ene compounds (II) and sulfohydrazide compounds (III), and the (E)-alkenyl sulfone compounds (I) are prepared. The method has the beneficial effects that the peroxidation reagent geminal diol peroxide compounds (V) are generated in situ, and operation is safe; iodide ions generated after I2 reaction are reoxidized by H2O2 in the presence of p-TsOH, and I2 is generated in situ and is involved in the reaction cyclically.
Silver-Catalyzed Denitrative Sulfonylation of β-Nitrostyrenes: A Convenient Approach to (E)-Vinyl Sulfones
Keshari, Twinkle,Kapoorr, Ritu,Yadav, Lal Dhar S.
supporting information, p. 2695 - 2699 (2016/06/08)
The first utilization of β-nitrostyrenes (readily available by the Henry reaction) for a highly stereoselective, convenient, and catalytic synthesis of (E)-vinyl sulfones at room temperature was investigated. The protocol involves efficient silver-catalyz
