138154-63-9 Usage
Molecular structure
A 2,3-dihydro-1H-indole core with an iodophenylmethyl substituent attached
Derivative of
Tryptophan (an amino acid)
Primary use
Research and drug development
Potential biological activity
Being studied for its potential use in the treatment of various diseases, including cancer and neurological disorders
Use as a precursor
In the synthesis of other pharmaceutical compounds
Unique property
As an iodinated indole derivative, it has the potential to interact with biological systems in unique ways
Value in research
It is a valuable tool for studying the molecular mechanisms of disease and for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 138154-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,1,5 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 138154-63:
(8*1)+(7*3)+(6*8)+(5*1)+(4*5)+(3*4)+(2*6)+(1*3)=129
129 % 10 = 9
So 138154-63-9 is a valid CAS Registry Number.
138154-63-9Relevant academic research and scientific papers
Samarium Diiodide Mediated Alkylation of Saturated Heterocycles alpha to Nitrogen
Booth, Susan E.,Benneche, Tore,Undheim, Kjell
, p. 3665 - 3674 (2007/10/02)
A method for α-alkylation of saturated 5-, 6-, 7- and 8-membered aza-heterocycles is described.The auxiliary is an o-iodobenzyl group attached at the nitrogen.A radical introduced in the o-position is transferred to the amine α-position which subsequently leads to an addition reaction with pentan-3-one.
Generation and Alkylation of Carbanions α to the Nitrogen of Amines by a New Metalation Procedure
Murakami, Masahiro,Hayashi, Minoru,Ito, Yoshihiko
, p. 793 - 794 (2007/10/02)
Treatment of a tertiary amine having a pendent o-iodobenzyl group on nitrogen with SmI2 generates α-amino organosamarium, which reacts with electrophiles giving the corresponding C-C bond formation products in good yield.
