1381803-89-9

Basic information

• Product Name: C₁₇H₁₆N₂O
• Synonyms: C₁₇H₁₆N₂O
• CAS NO: 1381803-89-9
• Molecular Weight: 264.327
• Mol File: 1381803-89-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₆N₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₆N₂O(1381803-89-9)
• EPA Substance Registry System: C₁₇H₁₆N₂O(1381803-89-9)

Safety Data

• Hazardous Substances Data: 1381803-89-9(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 4355-46-8 α-amino-α-methylphenylacetonitrile 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 1381802-78-3 4-amino-5-methyl-3,5-diphenyl-1H-pyrrol-2(5H)-one 

Relevant articles and documents

Approaches to the construction of substituted 4-amino-1 H -pyrrol-2(5 H)-ones

Fully substituted 4-aminopyrrolones are easily accessed via simple routes starting from imines, ketones, or α-bromophenyl acetonitriles. Imines were reacted with KCN/NH4Cl in aqueous ethanol to produce α-arylamino benzyl cyanides. On the other hand, ketones were transformed to the desired α-amino nitriles using a modified Strecker reaction. Then, α-amino nitrile precursors were allowed to react with a suitable acyl halide to produce the corresponding amides. Further treatment of these amides with ethanolic KOH converted them to highly substituted 4-amino-1H-pyrrol-2(5H)- one derivatives in moderate to excellent yields.