C₁₇H₁₆N₂O

Base Information

• Chemical Name: C₁₇H₁₆N₂O
• CAS No.: 1381803-89-9
• Molecular Formula: C₁₇H₁₆N₂O
• Molecular Weight: 264.327
• Mol file: 1381803-89-9.mol

Synonyms:C₁₇H₁₆N₂O

Chemical Property of C₁₇H₁₆N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₆N₂O

There total 2 articles about C₁₇H₁₆N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetophenone (98-86-2) → C17H16N2O (1381803-89-9)

Guidance literature:

Multi-step reaction with 2 steps

1: cetyltrimethylammonim bromide; ammonium chloride / ethanol; water / 8 h / 60 °C

2: 1,4-dioxane / 3 h / 20 - 110 °C

With cetyltrimethylammonim bromide; ammonium chloride; In 1,4-dioxane; ethanol; water;

DOI:10.1021/jo3004309

Reference yield:

α-amino-α-methylphenylacetonitrile (4355-46-8) + phenylacetyl chloride (103-80-0) → C17H16N2O (1381803-89-9)

Guidance literature:

In 1,4-dioxane; at 20 - 110 ℃; for 3h;

DOI:10.1021/jo3004309

Reference yield: 78.0%

C17H16N2O (1381803-89-9) → 4-amino-5-methyl-3,5-diphenyl-1H-pyrrol-2(5H)-one (1381802-78-3)

Guidance literature:

C₁₇H₁₆N₂O; With potassium hydroxide; In ethanol; at 75 ℃; for 0.75h;

With water; In ethanol;

DOI:10.1021/jo3004309

upstream raw materials:

acetophenone

α-amino-α-methylphenylacetonitrile

phenylacetyl chloride

Downstream raw materials:

4-amino-5-methyl-3,5-diphenyl-1H-pyrrol-2(5H)-one

Refernces