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1381949-81-0

C21H32N4O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1381949-81-0 Structure

  • Basic information

    1. Product Name: C21H32N4O2
    2. Synonyms:
    3. CAS NO:1381949-81-0
    4. Molecular Formula:
    5. Molecular Weight: 372.511
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1381949-81-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C21H32N4O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C21H32N4O2(1381949-81-0)
    11. EPA Substance Registry System: C21H32N4O2(1381949-81-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1381949-81-0(Hazardous Substances Data)

1381949-81-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1381949-81-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,1,9,4 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1381949-81:
(9*1)+(8*3)+(7*8)+(6*1)+(5*9)+(4*4)+(3*9)+(2*8)+(1*1)=200
200 % 10 = 0
So 1381949-81-0 is a valid CAS Registry Number.

1381949-81-0Downstream Products

1381949-81-0Relevant articles and documents

The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity

Cumming, John G.,Bower, Justin F.,Waterson, David,Faull, Alan,Poyser, Philip J.,Turner, Paul,McDermott, Benjamin,Campbell, Andrew D.,Hudson, Julian,James, Michael,Winter, Jon,Wood, Christine

, p. 3895 - 3899 (2012/07/03)

A novel N-aryl piperazine-1-carboxamide series of human CCR2 chemokine receptor antagonists was discovered. Early analogues were potent at CCR2 but also inhibited the hERG cardiac ion channel. Structural modifications which decreased lipophilicity and basicity resulted in the identification of a sub-series with an improved margin over hERG. The pharmacological and pharmacokinetic properties of the lead compound from this series, N-(3,4-dichlorophenyl)-4-[(2R)-4-isopropylpiperazine-2-carbonyl] piperazine-1-carboxamide, are described.

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