138343-92-7 Usage
Uses
Used in Pharmaceutical Industry:
(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID is used as a pharmaceutical intermediate for the synthesis of various medicinal compounds. The presence of the fluorine and amino groups suggests potential pharmacological activity, making it a valuable component in the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, (2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID is used as a building block for creating more complex molecules. The tert-butoxycarbonyl group serves as a protective group, temporarily masking reactive functional groups during synthesis, while the acetic acid moiety allows for its use as an acetylating agent.
Used in Chemical Research:
(2-TERT-BUTOXYCARBONYLAMINO-6-FLUORO-PHENYL)-ACETIC ACID is also utilized in chemical research to study its properties and potential applications. Further research and experimentation are necessary to fully understand the compound's characteristics and how it can be applied in various scientific and industrial contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 138343-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,3,4 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 138343-92:
(8*1)+(7*3)+(6*8)+(5*3)+(4*4)+(3*3)+(2*9)+(1*2)=137
137 % 10 = 7
So 138343-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H16FNO4/c1-13(2,3)19-12(18)15-10-6-4-5-9(14)8(10)7-11(16)17/h4-6H,7H2,1-3H3,(H,15,18)(H,16,17)
138343-92-7Relevant academic research and scientific papers
Process for the preparation of indolin-2-one derivatives useful as PR modulators
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Page/Page column 19, (2010/11/30)
Processes for dialkylating indolinones, specifically indolin-2-ones are provided. The processes for dialkylating an indolin-2-one include performing the dialkylation in the presence of at least 2 equivalents of a first base, a second base containing at le
Preparation of indoles and oxindoles from N-(tert-butoxycarbonyl)-2-alkylanilines
Clark,Muchowski,Fisher,Flippin,Repke,Souchet
, p. 871 - 878 (2007/10/02)
Treatment of dilithiated N-(tert-butoxycarbonyl)anilines 1 with dimethylformamide or carbon dioxide furnishes intermediates 3, 5, that are easily converted to N-(tert-butoxycarbonyl)indoles 4 and oxindoles (indol-2(3H)-ones, 7), respectively. Condensation of dilithiated 1 with N-methoxy-N-methylamides provides ketones 9 which are cyclized upon trifluoroacetic acid treatment to either 2-substituted 1-(tert-butoxycarbonyl)indoles 10 or 2-substituted indoles 11 depending on the reaction time. This general methodology has been applied to efficient synthesis of 1,2-alkyl-bridged indoles 12, 1,3,4,5-tetrahydrobenz[c,d]indole (16), 2a,3,4,5-tetrahydrobenz[c,d]indol-2(1H)-one (18), and 1-(tert-butoxycarbonyl)1H-pyrrolo[2,3-b]pyridine (21).
