1383734-85-7

Basic information

• Product Name: C₁₃H₁₀FN₃
• Synonyms: C₁₃H₁₀FN₃
• CAS NO: 1383734-85-7
• Molecular Weight: 227.241
• Mol File: 1383734-85-7.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₀FN₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₀FN₃(1383734-85-7)
• EPA Substance Registry System: C₁₃H₁₀FN₃(1383734-85-7)

Safety Data

• Hazardous Substances Data: 1383734-85-7(Hazardous Substances Data)

Upstream product

• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 87674-20-2 1-(3-fluoropyridin-2-yl)ethanone 
• 1383734-84-6 C₁₃H₁₁BrFN₃ 
• 111043-09-5 1-(3-bromopyridin-2-yl)ethanone 
• 1383734-83-5 1-(3-bromopyridin-2-yl)ethanol 
• 405174-97-2 3-bromopicolinaldehyde 

Downstream Products

• 1383735-43-0 1-(4-fluorophenyl)-3-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine 

Relevant articles and documents

ANTAGONISTS OF CHEMOKINE RECEPTORS

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.