1383734-83-5Relevant academic research and scientific papers
MODULATORS OF HEMOGLOBIN
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Paragraph 0463-0464, (2020/06/08)
The present disclosure relates generally to compounds and pharmaceutical compositions suitable as modulators of hemoglobin, and methods for their use in treating disorders mediated by hemoglobin.
Scalable and Straightforward Synthesis of All Isomeric (Cyclo)alkylpiperidines
Subota, Andrii I.,Lutsenko, Anton O.,Vashchenko, Bohdan V.,Volochnyuk, Dmitriy M.,Levchenko, Vitalina,Dmytriv, Yurii V.,Rusanov, Eduard B.,Gorlova, Alina O.,Ryabukhin, Sergey V.,Grygorenko, Oleksandr O.
, p. 3636 - 3648 (2019/06/13)
An efficient approach towards introducing (cyclo)alkyl substituents at C-2, C-3 or C-4 positions of the piperidine ring was described. The method relied on the straightforward two-step reaction sequence based on the formal sp3–sp3 re
PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS
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Page/Page column 50, (2012/07/13)
Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.
