1383801-45-3

Basic information

• Product Name: (+/-)-6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinic acid
• Synonyms: (+/-)-6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinic acid
• CAS NO: 1383801-45-3
• Molecular Weight: 456.467
• Mol File: 1383801-45-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinic acid(1383801-45-3)
• EPA Substance Registry System: (+/-)-6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinic acid(1383801-45-3)

Safety Data

• Hazardous Substances Data: 1383801-45-3(Hazardous Substances Data)

Upstream product

• 1383801-42-0 (+/-)-methyl 6-[(cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methyl)amino]nicotinate 
• 1383801-39-5 (+/-)-1-cyclohexyl-1-{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methanamine 
• 1383801-36-2 cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methanone 
• 1383801-33-9 (+/-)-cyclohexyl{2-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}methanol 
• 1427-06-1 methyl 6-fluoropyridine-3-carboxylate 
• 455-18-5 4-CF₃C₆H₄CN 
• 403-45-2 6-fluoronicotinic acid 
• 38980-96-0 4-(trifluoromethyl)benzimidamide hydrochloride 

Relevant articles and documents

Glucagon Receptor Modulators

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.