1384445-25-3

Upstream product

• 18704-37-5 quinoline-8-sulfonyl chloride 
• 94-09-7 p-aminoethylbenzoate 
• 150-13-0 4-amino-benzoic acid 
• 208175-71-7 ethyl 4-(quinoline-8-sulfonamido)benzoate 
• 116834-64-1 4-(quinoline-8-sulfonamido)benzoic acid 
• 3920-50-1 3-formylpyrazole 
• 1260081-87-5 N-(4-(piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide 
• 1260081-86-4 tert-butyl 4-(4-(quinoline-8-sulfonamido)benzoyl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

Pyruvate kinase activators for use in therapy

Described herein are methods for using compounds that activate pyruvate kinase.

THERAPEUTIC COMPOUNDS AND COMPOSITIONS

Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.