138469-76-8Relevant articles and documents
Active and Recyclable Catalytic Synthesis of Indoles by Reductive Cyclization of 2-(2-Nitroaryl)acetonitriles in the Presence of Co-Rh Heterobimetallic Nanoparticles with Atmospheric Hydrogen under Mild Conditions
Choi, Isaac,Chung, Hyunho,Park, Jang Won,Chung, Young Keun
supporting information, p. 5508 - 5511 (2016/11/17)
A cobalt-rhodium heterobimetallic nanoparticle-catalyzed reductive cyclization of 2-(2-nitroaryl)acetonitriles to indoles has been achieved. The tandem reaction proceeds without any additives under the mild conditions (1 atm H2 and 25 °C). This procedure could be scaled up to the gram scale. The catalytic system is significantly stable under these reaction conditions and could be reused more than ten times without loss of catalytic activity.
Synthesis of C3-substituted 4-azaindoles: An easy access to 4-azamelatonin and protected 4-azatryptophan
Jeanty, Matthieu,Suzenet, Franck,Guillaumet, Gerald
supporting information; experimental part, p. 7390 - 7393 (2009/05/07)
(Chemical Equation Presented) C3-Substituted-4-azaindoles were synthesized from pyridylacetonitriles in a two-step sequence allowing the easy introduction of a range of substituents. This strategy permits the rapid synthesis of 4-azamelatonin and a protec
THE USE OF o-NITROARYLACETONITRILES AS CARBON ACID PARTICIPANTS IN THE MITSUNOBU REACTION
Macor, John E.,Wehner, Jennifer M.
, p. 7195 - 7198 (2007/10/02)
The use of o-nitroarylacetonitriles as carbon acids in the Mitsunobu reaction is discussed as a method of carbon-carbon bond formation.This reaction represents a rare example of a carbon acid participating in a Mitsunobu reaction.