138474-49-4

Basic information

• Product Name: 3-Thiophenecarboxaldehyde, 2-(phenylmethyl)-
• CAS NO: 138474-49-4
• Molecular Formula: C12H10OS
• Molecular Weight: 202.277
• Mol File: 138474-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Thiophenecarboxaldehyde, 2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarboxaldehyde, 2-(phenylmethyl)-(138474-49-4)
• EPA Substance Registry System: 3-Thiophenecarboxaldehyde, 2-(phenylmethyl)-(138474-49-4)

Safety Data

• Hazardous Substances Data: 138474-49-4(Hazardous Substances Data)

Upstream product

• 138474-48-3 2-benzyl-3-bromothiophene 
• 68-12-2 N,N-dimethyl-formamide 
• 26137-09-7 2-(α-hydroxybenzyl)-3-bromothiophene 
• 100-52-7 benzaldehyde 
• 100-39-0 benzyl bromide 
• 17303-83-2 3-formylthiophene-2-boronic acid 

Downstream Products

• 138474-51-8 2-benzyl-3-(α-methoxybenzyl)thiophene 
• 138474-50-7 2-benzyl-3-(α-hydroxybenzyl)thiophene 

Relevant articles and documents

Ultrasound assisted Bradsher reaction in aqueous and non-aqueous media: First use of ultrasounds in electrophilic aromatic cyclisation leading to polyacenes

The present work describes the first use of ultrasounds in the Bradsher cyclisation of activated and non-activated ortho-formyl diarylmethanes. This reaction is also the first example of electrophilic, aromatic cyclisation assisted by ultrasounds which leads to pure polycyclic, fused aromatic hydrocarbons containing 3 and 4 fused rings in excellent yields. The reaction proceeds not only in aqueous but also in non-aqueous media at milder conditions (room temperature) and in much shorter reaction times than in conventional protocols.