138479-68-2Relevant academic research and scientific papers
Palladium-catalyzed acylation of 2-aryl-1,2,3-triazoles with aldehydes
Wang, Zechao,Tian, Qinshan,Yu, Xin,Kuang, Chunxiang
, p. 961 - 966 (2014)
The palladium-catalyzed acylation of 2-aryl-1,2,3-triazoles with aldehydes via C-H bond activation is described. A wide variety of products was isolated in good to excellent yields. This finding provides a new and useful strategy for the synthesis of aromatic ketones.
Regioselective ortho-Acylation of N-Aryl-1,2,3-triazoles with Alcohols in Water
Premi, Chanchal,Patel, Shyam Sunder,Jain, Nidhi
, p. 3788 - 3795 (2016/08/16)
A palladium-catalyzed regioselective ortho-acylation of N-aryl-1,2,3-triazoles has been achieved under aqueous conditions without the assistance of surfactants or additives. The reaction takes place by using benzylic, heterocyclic, and aliphatic alcohols as the acylating reagents and tert-butyl hydroperoxide (TBHP) as the oxidant and provides an alternative route for the synthesis of triazole-substituted aryl, heteroaryl, and aliphatic ketones in moderate to excellent yields.
Cyclization Reactions in Azole Chemistry: The Reaction of Some Azoles with o-Fluoroacetophenone, o-Fluorobenzaldehyde and o-Fluorobenzophenone
Rosevear, Judi,Wilshire, John F. K.
, p. 1097 - 1114 (2007/10/02)
The reactions of some azoles with o-fluoro-acetophenone, -benzaldehyde and -benzophenone in dimethyl sulfoxide solution in the presence of anhydrous potassium carbonate have been investigated.In addition to the expected substitution products, cyclization
