138495-06-4

Upstream product

• 100-52-7 benzaldehyde 
• 4138-35-6 methyl 3-aminopropanoate 

Downstream Products

• 138495-12-2 1-methoxycarbonyl-2-phenylpyrrolidin-3-one 
• 138495-09-7 3-Methoxy-2-phenyl-3-trimethylsilanyloxy-pyrrolidine-1-carboxylic acid methyl ester 
• 801282-28-0 1-Boc-2-phenylpyrrolidin-3-one 
• 1027391-26-9 3-methoxy-2-phenyl-3-trimethylsilanyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 23574-01-8 3-benzylamino-propionic acid methyl ester 
• 1430217-79-0 methyl 3-(N-benzyl-3-oxobutanamido)propanoate 
• 1430217-80-3 3-acetyl-1-benzyl-4-hydroxy-5,6-dihydropyridin-2(1H)-one 
• 1430217-81-4 5-benzyl-1,3-dimethyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-4(5H)-one 
• 1430217-82-5 5-benzyl-2,3-dimethyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridin-4(5H)-one 
• 1430217-83-6 5-benzyl-1,3-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine 
• 1430217-84-7 5-benzyl-2,3-dimethyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine 

Relevant academic research and scientific papers

SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Electroreductive intramolecular coupling of aromatic β- and γ-imino esters: A new synthetic method for N-alkoxycarbonyl-2-aryl-3-ones and cis-2-aryl-3-ols of pyrrolidines and piperidines

The electroreduction of aromatic β- and γ-imino esters prepared from β-alanine and GABA in the presence of chlorotrimethylsilane and subsequent N-alkoxycarbonylation of the resulting five- and six-membered cyclized amines gave mixed ketals of N-alkoxycarb