1384956-22-2Relevant academic research and scientific papers
Ni-catalyzed alkenylation of triazolopyridines: Synthesis of 2,6-disubstituted pyridines
Liu, Sheng,Sawicki, James,Driver, Tom G.
supporting information; experimental part, p. 3744 - 3747 (2012/08/28)
A synthetic strategy to access 2,6-disubstituted pyridines from triazolopyridines through a regioselective nickel-catalyzed alkenylation reaction of the C7-H bond is described. The N2 fragment embedded in the resulting C-H functionalized triazolopyridine can be readily excised using acidic or oxidative conditions to unmask the pyridine.
