1384973-99-2

Upstream product

• 85-44-9 phthalic anhydride 
• 123-08-0 4-hydroxy-benzaldehyde 
• 126-81-8 dimedone 
• 3645-45-2 phthaloyldihydrazine 
• 136918-14-4 phthalimide 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 

Relevant academic research and scientific papers

Phosphotungstic acid supported on SiO2@NHPhNH2 functionalized nanoparticles of MnFe2O4 as a recyclable catalyst for the preparation of tetrahydrobenzo[b]pyran and indazolo[2,1-b]phthalazine-triones

MnFe2O4@SiO2@NHPhNH2–phosphotungstic acid was synthesized by the reaction of diamine-modified silica coated manganese ferrite nanoparticles with H3PW12O40, the Keggin-type hetero

One-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones via nano γ-Al2O3/BF3/Fe3O4 as an efficient catalyst and theoretical DFT study on them

Experimental and computational studies were carried out for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones using γ-Al2O3/BF3/Fe3O4 as a nanocatalyst in optimized and solvent-free conditions. The most significant features of the existing protocol are easy preparation of the catalyst, short reaction times, environmentally benign, and milder reaction conditions. The analysis data were reported using the experimental results of this investigation, such as: H-NMR, FT-IR (Fourier-transform infrared spectroscopy), X-ray diffraction, vibrating-sample magnetometer, Thermal gravimetric analysis (TG-DTG), nitrogen adsorption isotherm, Field Emission Scanning Electron Microscopy, and Transmission electron microscopy images of nanocatalyst. In this study, 2H-indazolo[2,1-b]phthalazine-triones have also been theoretically investigated using DFT-B3LYP/6-31G method. Also, some of the physical chemistry properties have examined for conformers of products, which there was good agreement between the computational results and obtained experimental for the products.

Application of O-sulfonic acid poly(4-vinylpyrrolidonium) chloride as an efficient polymer-supported catalyst in the rapid synthesis of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products

In this work, a series of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products were efficiently synthesized for the first time using O-Sulfonic acid poly(4-vinylpyrrolidonium) chloride ([PVP-SO3H]Cl) as an eco-friendly polymer-supp

Synthesis of phthalazine compounds using heterogeneous base catalyst based on silica nanoparticles obtained from rice husk

In this study, the nanoparticles of amorphous silica were easily extracted from low-cost rice husk ash. They were functionalized with 3-(chloropropyl) trimethoxysilane by incorporating chloropropyl groups directly through the condensation of nanosilica an

Deep eutectic solvent an efficient reaction medium for the synthesis of chromeno pyrazolo and indazolo phthalazine derivatives

The volatile, harmful and hazardous solvents have impact on human health, all organisms and environment. To reduce the use of hazardous volatile solvents, there is need to develop the alternative green reaction medium for organic transformations and is th

Green one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones: a comparative study of heterogeneous solid acid catalysts with magnetic core

The catalytic activity of four heterogeneous solid acid catalysts with magnetic core and sulfonic acid groups is evaluated and compared using one-pot three component synthesis of phthalazine-trione derivatives under solvent-free condition. The NiFe2

Pentaerythritol as efficient H-bonding organocatalyst for synthesis of indazolo[2,1-b]phthalazine-trione derivatives

Pentaerythritol was applied as an effective, biodegradable, nontoxic, mild, and commercially available H-bonding organocatalyst for synthesis of indazolo[2,1-b]phthalazine-trione derivatives via one-pot three-component condensation of aromatic aldehydes,

Phthalazine-trione as a blue-green light-emitting moiety: Crystal structures, photoluminescence and theoretical calculations

Phthalazine (2,3-diazanaphthalene) and phthalhydrazide (2,3-dihydro-1,4-phthalazinedione) compounds are heterocycles with several biological properties. Most recently, analogous phthalazine-triones also emerged as drug candidates. Herein, we introduced a

[Bu3NH][HSO4] catalyzed: an eco-efficient synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones and 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

A Br?nsted acidic ionic liquid [Bu3NH][HSO4] as an eco-efficient catalyst for the one-pot multicomponent synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones and 2H-indazolo[2,1-b]phthalazine-triones by using various aldehyde, malo

Synthesis, characterization and in vitro antibacterial activity of novel phthalazine sulfonamide derivatives

Several phthalazine derivatives were synthesized by the one-pot three-component condensation in good to high yields in the presence of diatomite-SO 3H as a solid acid catalyst. Then, a series (n?=?14) of phthalazine sulfonamides were synthesize