138538-42-8 Usage
General Description
4-Pyrimidinecarboxylic acid, 6-methyl- (9CI) is a chemical compound with the molecular formula C6H5N3O2. It is a derivative of pyrimidinecarboxylic acid, with a methyl group attached to the 6th carbon atom. 4-Pyrimidinecarboxylic acid, 6-methyl- (9CI) is an important intermediate in the synthesis of various pharmaceuticals and organic compounds. It is commonly used as a building block in the preparation of pyrimidine-based drugs and agrochemicals. 4-Pyrimidinecarboxylic acid, 6-methyl- (9CI) is also known for its potential biological activities, including anti-inflammatory and anti-tumor properties, making it a subject of interest in medical research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 138538-42-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,3 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 138538-42:
(8*1)+(7*3)+(6*8)+(5*5)+(4*3)+(3*8)+(2*4)+(1*2)=148
148 % 10 = 8
So 138538-42-8 is a valid CAS Registry Number.
138538-42-8Relevant articles and documents
Reaction of β-alkoxyvinyl α-ketoesters with acyclic NCN binucleophiles – Scalable approach to novel functionalized pyrimidines
Stepaniuk, Oleksandr O.,Rudenko, Tymofii V.,Vashchenko, Bohdan V.,Matvienko, Vitalii O.,Kondratov, Ivan S.,Tolmachev, Andrey A.,Grygorenko, Oleksandr O.
supporting information, p. 3472 - 3478 (2019/05/17)
Two protocols for synthesis of series of low-molecular-weight di- and tri-substituted pyrimidines bearing a functional group at the 4th position, which rely on a base-mediated condensation of amidines or guanidines with β-alkoxyvinyl α-keto esters, have been developed. This approach allowed for multigram preparation of novel pyrimidine-4-carboxylates in 21–90% yield. The synthetic utility of these compounds was demonstrated by some standard functional group transformations providing promising building blocks for organic synthesis and drug discovery.