138560-19-7

Basic information

• Product Name: 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-ido-hept-6-enose
• Synonyms: 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-ido-hept-6-enose
• CAS NO: 138560-19-7
• Molecular Weight: 536.668
• Mol File: 138560-19-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-ido-hept-6-enose(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-ido-hept-6-enose(138560-19-7)
• EPA Substance Registry System: 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-ido-hept-6-enose(138560-19-7)

Safety Data

• Hazardous Substances Data: 138560-19-7(Hazardous Substances Data)

Upstream product

• 1417606-42-8 2-((1S,2R,3S,4R)-1,2,3,4-tetra(benzyloxy)hex-5-en-1-yl)thiazole 
• 1417606-25-7 (1S,2S,3S,4R)-2,3,4-tris(benzyloxy)-1-(2-thiazolyl)hex-5-en-1-ol 
• 1417606-26-8 C₃₀H₂₉NO₄S 
• 100-39-0 benzyl bromide 
• 73111-58-7 2,3,4-tri-O-benzyl-5,6-dideoxy-D-xylo-hex-5-enose 
• 138560-18-6 6,7-dideoxy-2,3,4,5-tetrakis-O-(phenylmethyl)-D-gulo/ido-hept-6-enose, cyclic 1,3-propanediyl mercaptals 

Downstream Products

• 138662-25-6 (+)-(3aα,4β,5α,6β,7α)-3,3a,4,5,6,7-hexahydro-4,5,6,7-tetrakis(phenylmethoxy)-2,1-benzisoxazole 
• 138560-25-5 (-)-(3aα,4α,5β,6α,7β)-3,3a,4,5,6,7-hexahydro-4,5,6,7-tetrakis(phenylmethoxy)-2,1-benzisoxazole 
• 1417606-43-9 (2S,3R,4S,5R)-2,3,4,5-tetra(benzyloxy)hept-6-enoic acid 
• 1417606-44-0 (2S,3R,4S,5R)-2,3,4,5-tetra(benzyloxy)-N-((S)-2-oxoazepa-3-yl)hept-6-enamide 
• 1417606-45-1 (2S,3R,4S,5R,E)-2,3,4,5-tetra(benzyloxy)-8-methyl-N-((S)-2-oxoazepan-3-yl)non-6-enamide 
• 138662-23-4 1,2-dideoxy-2-(hydroxymethyl)-1-(methylamino)-scyllo-inositol 
• 138560-22-2 (1R,2S,3S,4R,5S,6S)-5-(hydroxymethyl)-6-(methylamino)cyclohexane-1,2,3,4-tetraol hydrochloride 
• 138662-22-3 (3aα,4α,5β,6α,7β,7aβ)-octahydro-1-methyl-4,5,6,7-tetrakis(phenylmethoxy)-2,1-benzisoxazole 
• 138560-21-1 (-)-(3aα,4β,5α,6β,7α,7aα)-octahydro-1-methyl-4,5,6,7-tetrakis(phenylmethoxy)-2,1-benzisoxazole 
• 138560-24-4 2-<(acetyl)amino>-2,3-dideoxy-3-(hydroxymethyl)-1,4,5,6-tetrakis-O-(phenylmethyl)-D-myo-inositol 

Relevant articles and documents

Concise synthesis and antitumor activity of Bengamide e and its analogs

Bengamide E (1a) and C-2 epimer (1b), free hydroxyl analogs (1c) and (1d), and shorter chain analog (1e) were synthesized by utilizing (2R,3S,4R)-2,3,4- tris(benzyloxy)hex-5-enal (2a) as the chiral building block. Preliminary biological studies revealed that only compound 1c showed slightly weaker activity than Bengamide E (1a) against MDA-MB-453 human breast carcinoma cells, MCF-7 human breast cancer cells and HCT-116 colon cancer cells, with the others being inactive. These results suggest that the correct stereochemistry at C-2, the alkylation on C-2 hydroxyl group, as well as the length of the carbon chain of Bengamide E are critical for structural recognition and binding to the target(s).

Diastereoselectivity in the intramolecular nitrone, oxime, and nitrile oxide cycloaddition reactions. Synthesis of amino inositol derivatives as α-glucosidase inhibitors

The diastereoselectivity in the intramolecular 1,3-dipolar cycloaddition reactions of 4 and 5 (R=Bn, 4-MeOBn) was examined.