138571-54-7

Upstream product

• 138571-53-6 N⁶-benzoyl-9<(1R,2S,3R)-4-(1-hydroxyethyl)-2,3-(isopropylidenodioxy)-4-cyclopenten-1-yl>adenine 
• 400611-65-6 N-{9-[4,5-bis-(tert-butyl-dimethyl-silanyloxy)-3-(1-hydroxy-ethyl)-cyclopent-2-enyl]-9H-purin-6-yl}-benzamide 
• 138571-49-0 N⁶-benzoyl-9-<(1R,2S,3R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)-4-cyclopenten-1-yl>adenine 
• 138571-50-3 N⁶-benzoyl-9<(1R,2S,3R)-4-formyl-2,3-(isopropylidenedioxy)-4-cyclopenten-1-yl>adenine 
• 72877-50-0 neplanocin A 
• 400611-67-8 (6'S)-2',3'-di-O-(tert-butyldimethylsilyl)-6'-methylnaplanocin A 
• 83844-30-8 N⁶-benzoyl-9-<(1R,2S,3R)-2,3-dihydroxy-4-(hydroxymethyl)-4-cyclopenten-1-yl>adenine 
• 400611-68-9 (6'R)-2',3'-di-O-(tert-butyldimethylsilyl)-6'-methylnaplanocin A 
• 400611-62-3 2',3',6'-tri-O-(t-butyldimethylsilyl)-N⁶-benzoylneplanocin 
• 400611-63-4 2',3'-di-O-(t-butyldimethylsilyl)-N⁶-benzoylneplanocin 
• 400611-64-5 2',3'-di-O-(t-butyldimethylsilyl)-N⁶-benzoylneplanocin A 6'-aldehyde 

Downstream Products

• 138571-53-6 N-{9-[(3aS,4R,6aR)-6-((R)-1-Hydroxy-ethyl)-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-yl]-9H-purin-6-yl}-benzamide 

Relevant academic research and scientific papers

New neplanocin analogues. 12. Alternative synthesis and antimalarial effect of (6′R)-6′-C-methylneplanocin A, a potent AdoHcy hydrolase inhibitor

An improved method for the synthesis of (6′R)-6′-C-methylneplanocin A (RMNPA, 2), a potent S-adenosyl-L-homocysteine (AdoHcy) hydrolase inhibitor, was developed via a chelation-controlled stereoselective addition of MeTiCl3 to the neplanocin A

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents

Novel neplanocin A analogues modified at the 6'-position, i.e., 6'-deoxy analogues (2, 3, 6, 9, 20), 6'-O-methylneplanocin A (15), and 6'-C- methylneplanocin A's (22a and 22b) have been synthesized and evaluated for their antiviral activity in a wide vari