138571-50-3

Upstream product

• 83844-30-8 N⁶-benzoyl-9-<(1R,2S,3R)-2,3-dihydroxy-4-(hydroxymethyl)-4-cyclopenten-1-yl>adenine 
• 98-88-4 benzoyl chloride 
• 72877-50-0 neplanocin A 
• 138571-49-0 N⁶-benzoyl-9-<(1R,2S,3R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)-4-cyclopenten-1-yl>adenine 

Downstream Products

• 138571-54-7 6'-(R)-methylneplanocin A 
• 138662-99-4 6'-(S)-methylneplanocin A 
• 179929-35-2 (3aR,6R,6aS)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-6,6a-dihydro-3aH-cyclopenta[1,3]dioxole-4-carboxylic acid methylamide 
• 179929-33-0 (3aR,6R,6aS)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-6,6a-dihydro-3aH-cyclopenta[1,3]dioxole-4-carboxylic acid amide 
• 194353-42-9 (6'R)-N⁶-benzoyl-6'-C-ethynyl-2',3'-O-isopropylideneneplanocin A 
• 138571-51-4 N⁶-benzoyl-9<(1R,2S,3R)-4-ethenyl-2,3-(isopropylidenedioxy)-4-cyclopenten-1-yl>adenine 
• 138571-53-6 N⁶-benzoyl-9<(1R,2S,3R)-4-(1-hydroxyethyl)-2,3-(isopropylidenodioxy)-4-cyclopenten-1-yl>adenine 

Relevant academic research and scientific papers

New neplanocin analogues. V. A potent adenosylhomocysteine hydrolase inhibitor lacking antiviral activity. Synthesis and antiviral activity of 6′-carboxylic acid derivatives of neplanocin A

The 6′-carboxylic acid derivative of neplanocin A 3 was synthesized from NPA, and was converted to the corresponding methyl ester 4 and amides 5 and 6. These were evaluated for their anti-RNA-virus activities. Of the derivatives synthesized, only 5 was ac

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents

Novel neplanocin A analogues modified at the 6'-position, i.e., 6'-deoxy analogues (2, 3, 6, 9, 20), 6'-O-methylneplanocin A (15), and 6'-C- methylneplanocin A's (22a and 22b) have been synthesized and evaluated for their antiviral activity in a wide vari