138585-09-8

Basic information

• Product Name: 4-(tert-Butyldimethylsilyloxy)benzyl chloride
• Synonyms: 4-(tert-Butyldimethylsilyloxy)benzyl chloride
• CAS NO: 138585-09-8
• Molecular Formula: C₁₃H₂₁ClOSi
• Molecular Weight: 256.84
• Mol File: 138585-09-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(tert-Butyldimethylsilyloxy)benzyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(tert-Butyldimethylsilyloxy)benzyl chloride(138585-09-8)
• EPA Substance Registry System: 4-(tert-Butyldimethylsilyloxy)benzyl chloride(138585-09-8)

Safety Data

• Hazardous Substances Data: 138585-09-8(Hazardous Substances Data)

Usage

General Description

4-(tert-Butyldimethylsilyloxy)benzyl chloride is an organic chemical compound with the molecular formula C14H25ClOSi. It is a derivative of benzyl chloride, where the hydrogen atom on the benzene ring is replaced by a 4-(tert-butyldimethylsilyloxy) group. This chemical is commonly used in organic synthesis as a protecting group for alcohols to prevent unwanted reactions at the hydroxyl group during chemical reactions. It can also be used as a reagent for the introduction of the benzyl group into various organic compounds. 4-(tert-Butyldimethylsilyloxy)benzyl chloride is important in the field of organic chemistry and has various applications in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 124-63-0 methanesulfonyl chloride 
• 138585-08-7 (4-((tert-butyldimethylsilyl)oxy)phenyl)methanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 

Downstream Products

• 625848-58-0 1,1-diethoxy-3-(4-hydroxyphenyl)-2-propan-2-one 
• 123437-48-9 8-benzyl-6-(4-fluorophenyl)-2-(4-hydroxyphenylmethyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 1338220-17-9 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(thiophen-3-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-13-5 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(naphthalen-2-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-11-3 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(naphthalen-1-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-09-9 (E)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-styrylimidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-21-5 8-(benzo[b]thiophen-3-yl)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-19-1 8-(benzo[b]thiophen-2-yl)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1254472-47-3 C₁₇H₂₈O₃Si 
• 319016-05-2 4-[N-(4-hydroxybenzyl)-N-(4-methoxyphenyl)amino]benzonitrile 
• 55779-48-1 coelenterazine 
• 10589-27-2 3-(p-hydroxyphenyl)-2-oxopropanal 
• 625848-41-1 ethyl 4-(4-{[3-amino-6-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-2-pyrazinyl]methyl}phenoxy)butanoate 
• 625848-33-1 ethyl 4-{4-[(3-amino-6-bromo-2-pyrazinyl)methyl]phenoxy}butanoate 

Relevant articles and documents

FLUOROCHROME-COUPLED COELENTERAZINE

PROBLEM TO BE SOLVED: To provide techniques of making the light emission wavelength of a Renilla luciferase (Rluc)-coelenterazine light-emitting system longer by modifying coelenterazine. SOLUTION: A fluorochrome-coupled coelenterazine is represented by t

Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives w

COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES

Coelenterazine analogs with different luminescence properties from conventional ones and coelenteramide analogs with different fluorescence properties from conventional ones have been desired. The invention provides coelenterazine analogs modified at the