138617-82-0

Basic information

• Product Name: (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE
• Synonyms: (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE;1-[(1R)-1-isothiocyanatoethyl]-Naphthalene
• CAS NO: 138617-82-0
• Molecular Formula: C₁₃H₁₁NS
• Molecular Weight: 213.3
• EINECS: -0
• Mol File: 138617-82-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 354.4°Cat760mmHg
• Flash Point: 177.8°C
• Appearance: /
• Density: 1,155 g/cm3
• Vapor Pressure: 6.85E-05mmHg at 25°C
• Refractive Index: 1.6570
• Sensitive: Moisture Sensitive
• BRN: 8481207
• CAS DataBase Reference: (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(138617-82-0)
• EPA Substance Registry System: (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(138617-82-0)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2810
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 138617-82-0(Hazardous Substances Data)

Usage

General Description

(R)-(-)-1-(1-Naphthyl)ethyl isothiocyanate is a chemical compound with the molecular formula C13H9NS. It is an organic compound containing both isothiocyanate and naphthalene moieties. (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE is used in organic synthesis, particularly in the preparation of various organic compounds. It is known for its characteristic pungent odor and is commonly used as an insecticide and fungicide. Additionally, it has been studied for its potential pharmacological properties, including its potential use as an anticancer agent. The compound has also been investigated for its potential use in the development of new drugs and pharmaceuticals.

InChI:InChI=1/C13H11NS/c1-10(14-9-15)12-8-4-6-11-5-2-3-7-13(11)12/h2-8,10H,1H3/t10-/m1/s1

Upstream product

• 463-71-8 thiophosgene 
• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 
• 75-15-0 carbon disulfide 

Downstream Products

• 313695-81-7 N-[(1S,2S)-2-tert-butoxycarbonylamino-1,2-diphenylethyl]-N'-[(R)-1-(1-naphthyl)ethyl]thiourea 
• 313695-94-2 (4S,5S)-1-tert-butoxycarbonyl-4,5-diphenyl-2-[(R)-1-(1-naphthyl)ethylimino]imidazolidine 

Relevant articles and documents

Crystallographic, 1H NMR and CD studies of sterically strained thiourea anion receptors possessing two stereogenic centres

The synthesis and structural characterisation of three chiral bis-naphthalene thiourea receptors (1-3) derived from (R)-(+)-1-(1-naphthyl) ethylamine and (S)-(-)-1-(1-naphthyl)ethylamine are reported along with spectroscopic studies to screen their potential as anion receptors/sensors. Their solid state structures were analysed by X-ray crystallography and their ability to bind anions such as acetate and phosphate in DMSO solution investigated by 1H NMR, absorption, fluorescence and circular dichroism spectroscopy.

Highly enantioselective addition of ketones to nitroolefins catalyzed by new thiourea-amine bifunctional organocatalysts

A new and effective organocatalytic system: primary amine derived chiral thiourea catalyst 4a and AcOH-H2O additive, which converts different ketones to γ-nitroketones in high yields (82-99%) and enantioselectivities (90-99%) has been described

(R)-[1-(1-Naphthyl)ethyl] isothiocyanate and (S)-1-phenylethyl isothiocyanate. New chirality recognizing reagents for the determination of enantiomeric purity of chiral amines by NMR

(S)-1-Phenylethyl isothiocyanate and (R)-[1-(1-naphthyl)ethyl] isothiocyanate which are easily formed and stable in aqueous conditions are utilized as new chirality recognizing reagents for the determination of enantiomeric purity of chiral amines by NMR.