138711-46-3

Upstream product

• 138711-42-9 5-Acrylamido-6-methyl-3-phenylpyrimidin-4(3H)-one 
• 89966-52-9 5-(chloroacetylamino)-6-methyl-3-phenyl-4(3H)-pyrimidinone 
• 138711-45-2 6-Methyl-5-(p-nitrobenzamido)-3-phenylpyrimidin-4(3H)-one 
• 65765-92-6 5-amino-6-methyl-3-phenyl-4(3H)-pyrimidinone 
• 67-63-0 isopropyl alcohol 
• 64-17-5 ethanol 

Relevant academic research and scientific papers

Synthesis of 1H-Imidazoles by the Simple Ring Transformation of 5-Acylaminouracils and 5-Acylaminopyrimidin-4(3H)-ones

1,2-Disubstituted 4-alkylcarbamoyl-5-methyl-1H-imidazoles and 2-substituted 5-methyl-4-phenylcarbamoyl-1H-imidazoles were synthesized from 5-acylamino-6-methyluracils and 5-acylamino-6-methyl-3-phenylpyrimidin-4(3H)-ones by treatment with sodium hydroxide in ethanol.In the case of 5-acylaminopyrimidinones which possess an olefinic group in the acylamino group, 2-ethoxyethyl (or 2-ethoxypropyl)-5-methyl-4-phenylcarbamoyl-1H-imidazoles were prepared as major products and the corresponding 2-alkenyl-1H-imidazoles were only minor products.Compounds which contain an aryl function in their acylamino group gave glycine anilides as byproducts.