1387581-35-2Relevant academic research and scientific papers
Asymmetric double Michael reaction catalyzed by simple primary amine catalysts: A straightforward approach to construct spirocyclic oxindoles
Luo, Xiya,Wang, Liangliang,Peng, Lin,Bai, Jianfei,Jia, Lina,He, Guangyun,Tian, Fang,Xu, Xiaoying,Wang, Lixin
experimental part, p. 1185 - 1188 (2012/07/27)
The enantioselective double Michael reaction of N-Boc-3-nonsubstitued oxindoles with dienones catalyzed by chiral monoimide protected cyclohexane-1,2-diamines was developed. A wide range of optically active spirocyclic oxindoles were obtained up to 98% yield and up to 89% ee.
