138852-33-2Relevant academic research and scientific papers
A Bifunctional MOF Catalyst Containing Metal–Phosphine and Lewis Acidic Active Sites
Prasad, Ram R. R.,Dawson, Daniel M.,Cox, Paul A.,Ashbrook, Sharon E.,Wright, Paul A.,Clarke, Matthew L.
supporting information, p. 15309 - 15318 (2018/09/27)
Post-synthetic modification of the hafnium metal–organic framework MOF-808(Hf) to include triarylphosphine ligands is reported. Sulfonated phenylphosphines are incorporated without oxidation to give a “MOF ligand” that can complex late transition metals such as Ir and Rh to give a bifunctional catalyst containing both metal–phosphine complexes and the Lewis acidic framework hafnium metal sites. The metallated phosphine-bearing MOFs act as fully heterogeneous bifunctional catalysts for tandem reductive amination and hydroaminomethylation reactions.
Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid
Pan, Hui-Jie,Ng, Teng Wei,Zhao, Yu
supporting information, p. 5490 - 5493 (2016/07/06)
An iron-catalyzed transfer hydrogenation of N-aryl and N-alkyl imines using isopropanol as the hydrogen donor is reported for the first time. A combination of two iron complexes serving different roles is the key for the success of this catalytic system. As a result, an environmentally friendly and precious metal-free transfer hydrogenation of imines has been developed. The use of a suitable co-catalyst as an activator not only led to efficient transfer hydrogenation, but also showed potential in enantioselective transformation.
Sequential reductive amination-hydrogenolysis: A one-pot synthesis of challenging chiral primary amines
Nugent, Thomas C.,Negru, Daniela E.,El-Shazly, Mohamed,Hu, Dan,Sadiq, Abdul,Bibi, Ahtaram,Umar, M. Naveed
supporting information; experimental part, p. 2085 - 2092 (2011/10/19)
Difficult-to-access chiral primary amines were formed in good to high yield and ee using a rare example of a one-pot synthesis from prochiral ketones (sequential reductive amination-hydrogenloysis). As a highlight we also demonstrate a one-pot reductive amination-hydrogenolysis-reductive amination (five reactions) of ortho-methoxyacetophenone resulting in the chiral diamine 1-(2-methoxyphenyl)ethyl-(2-pyridylmethyl)-amine (4) (58% overall yield, >99% ee), a new organocatalyst for aqueous enantioselective aldol reactions. Copyright
A versatile catalyst for reductive animation by transfer hydrogenation
Wang, Chao,Pettman, Alan,Basca, John,Xiao, Jianliang
supporting information; experimental part, p. 7548 - 7552 (2010/12/19)
An iridium catalyst enables the reductive amination of carbonyl groups with unprecedented substrate scope, selectivity, and activity using formic acid as the hydrogen source (see scheme) The catalyst system provides significant improvement over commonly used boron hydrides.
