1388851-19-1

Basic information

• Product Name: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• Synonyms: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• CAS NO: 1388851-19-1
• Molecular Formula: C21H18N4O2
• Molecular Weight: 358.39322
• Mol File: 1388851-19-1.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(1388851-19-1)
• EPA Substance Registry System: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(1388851-19-1)

Safety Data

• Hazardous Substances Data: 1388851-19-1(Hazardous Substances Data)

Upstream product

• 89-25-8 edaravone 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 71-33-0 Allantoxaidin 
• 13401-18-8 1,3-Dimethyllumazine 
• 931-86-2 azacytosine 
• 7357-70-2 Cyanothioacetamide 
• 41927-23-5 4-bromo-3-methyl-1-phenylpyrazol-5-one 
• 122-51-0 orthoformic acid triethyl ester 
• 1380500-93-5 tert-butyl N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]carbamate 
• 75512-10-6 4-ethoxymethylene-1-phenyl-3-methyl pyrazolone 
• 74451-57-3 (E)-5,5'-dimethyl-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione 
• 68719-56-2 4-bromo-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 611-08-5 2,4-dihydroxy-5-nitropyrimidine 
• 132603-45-3 Z-1-phenyl-3-methyl-4-<(3-indolyl)methylene>-5-pyrazolone 

Relevant articles and documents

Reaction of 5-azacytosine with 3-methyl-1-phenyl-5-pyrazolone

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New Synthetic Potential of Pteridine Derivatives: Direct Substitution of H in 1,3-Dimethyllumazine During Reaction with C-Nucleophiles

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Interaction of fervenulin-4-oxide with 1-phenyl-3-methylpyrazol-5-one in the absence of bases

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Investigation of tetrazine reactivity towards C-nucleophiles: Pyrazolone-based modification of biomolecules

Chemoselective, biocompatible ligation reactions are the key components for efficient and modular access to biomolecular scaffolds. Tetrazine ligation leads to the formation of a mixture of isomers, which makes reaction monitoring, purification and characterization of conjugates difficult. We report herein a modified tetrazine ligation strategy based on the use of a pyrazolone coupling partner, which provides a single molecule conjugate.

Reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehydes with barbituric acids and 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Formation of compound with extremely short intramolecular hydrogen bond in eight-membered pseudocycle

New indolin-2-one derivatives, containing in its molecules eight-membered pseudo-cycle with unusually short intramolecular hydrogen bond in OHO-bridge have been synthesized by reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehyde with barbituric acids or 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Under the action of amines they undergo fragmentation to 5-aminomethylenebarbituric acids or 4-aminomethylenepyrazolones and 1-alkyl-1,3-dihydroindol-2-ones.