1388851-19-1

Basic information

• Product Name: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• Synonyms: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• CAS NO: 1388851-19-1
• Molecular Formula: C21H18N4O2
• Molecular Weight: 358.39322
• Mol File: 1388851-19-1.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(1388851-19-1)
• EPA Substance Registry System: 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(1388851-19-1)

Safety Data

• Hazardous Substances Data: 1388851-19-1(Hazardous Substances Data)

Upstream product

• 77287-34-4 formamide 
• 89-25-8 edaravone 
• 4316-93-2 4,6-dichloro-5-nitropyrimidine 
• 1380500-93-5 tert-butyl N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]carbamate 
• 7357-70-2 Cyanothioacetamide 
• 41927-23-5 4-bromo-3-methyl-1-phenylpyrazol-5-one 
• 611-08-5 2,4-dihydroxy-5-nitropyrimidine 
• 132603-45-3 Z-1-phenyl-3-methyl-4-<(3-indolyl)methylene>-5-pyrazolone 
• 931-86-2 azacytosine 
• 61466-08-8 5,5'-bis-(4-nitro-phenyl)-2,2'-diphenyl-1,2,2',4'-tetrahydro-4,4'-methanylylidene-bis-pyrazol-3-one 
• 61466-06-6 2,5,2',5'-tetraphenyl-1,2,2',4'-tetrahydro-4,4'-methanylylidene-bis-pyrazol-3-one 
• 62758-20-7 6,8-dimethyl-3,5,7-trioxo-2,3,5,6,7,8-hexahydropyrimido[5,4-e][1,2,4]-triazine-4-oxide 
• 122-51-0 orthoformic acid triethyl ester 

Relevant articles and documents

Reaction of 5-azacytosine with 3-methyl-1-phenyl-5-pyrazolone

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New Synthetic Potential of Pteridine Derivatives: Direct Substitution of H in 1,3-Dimethyllumazine During Reaction with C-Nucleophiles

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Interaction of fervenulin-4-oxide with 1-phenyl-3-methylpyrazol-5-one in the absence of bases

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Investigation of tetrazine reactivity towards C-nucleophiles: Pyrazolone-based modification of biomolecules

Chemoselective, biocompatible ligation reactions are the key components for efficient and modular access to biomolecular scaffolds. Tetrazine ligation leads to the formation of a mixture of isomers, which makes reaction monitoring, purification and characterization of conjugates difficult. We report herein a modified tetrazine ligation strategy based on the use of a pyrazolone coupling partner, which provides a single molecule conjugate.

Reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehydes with barbituric acids and 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Formation of compound with extremely short intramolecular hydrogen bond in eight-membered pseudocycle

New indolin-2-one derivatives, containing in its molecules eight-membered pseudo-cycle with unusually short intramolecular hydrogen bond in OHO-bridge have been synthesized by reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehyde with barbituric acids or 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Under the action of amines they undergo fragmentation to 5-aminomethylenebarbituric acids or 4-aminomethylenepyrazolones and 1-alkyl-1,3-dihydroindol-2-ones.