74451-57-3Relevant academic research and scientific papers
A versatile synthesis, PM3-semiempirical, antibacterial, and antitumor evaluation of some bioactive pyrazoles
Hamama, Wafaa S.,El-Gohary, Hamada G.,Soliman, Mamdouh,Zoorob, Hanfi H.
experimental part, p. 543 - 554 (2012/08/27)
This research work describes the synthesis and biological properties of some novel isolated or fused heterocyclic ring systems with pyrazole, for example; enaminones containing pyrazolone ring photochromic functional unit, 4-[(4-chlorophenylamino)methylene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (3) and some analogous derivatives 4, 9, and 10, also as pyrazolo[3,4-b]pyridine, pyrazolo[3,4-b]quinoline, pyrazolo[3',4':4,5]thieno[2,3-c]pyrazoline and pyrazolo[3,4-c]pyrazole were synthesized and characterized. Newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, mass spectral data and quantum mechanical calculations. Selected products were tested for their antibacterial and antitumor agents.
Free Radical Reactions of N-Heterocyclic Compounds. XI. Reaction of 3-Methyl-pyrazolin-5-ones with Phenoxy Radicals
Schulz, Manfred,Meske, Michael
, p. 607 - 615 (2007/10/02)
Pyrazolin-5-ones (3a-i) were oxidized with 2,4,6-trisubstituted phenoxy radicals (2a-d) to the corresponding radicals (4a-i), which dimerised or combined with phenoxy radical (2a) depending on the R1- and R4-substituents in (3).In th
About the Reaction of "Pyrazolone Blue" with Diazomethane
Hennig, L.,Haessner, R.,Rissanen, K.
, p. 584 - 590 (2007/10/02)
The reaction of "pyrazolone blue" with diazomethane was investigated.A pyridazinone derivative 3, a heterocyclic spiro-cyclopropyl product 4 and a compound 7, which contains three pyrazolone and two diazomethane entities, are formed. 3 reacts with an exce
Investigations on the Reaction of Pyrazolone Azomethine Dyes with 2-Pyrazolin-5-one-Derivatives
Kucybala, Z.,Gaca, J.
, p. 435 - 439 (2007/10/02)
The reaction between pyrazolone azomethine dyes 1 and different 2-pyrazolin-5-ones 2 was investigated.Among the reaction products compounds 5 > was isolated, which hitherto was unknown as a product of this reaction.A new reaction pathway is proposed.
Oxopyrazoline-spiro-oxirans. A New Class of Reactive Heterocycles
Ege, Seyhan N.,Adams, Alan. D.,Gess, E. Joseph,Ragone, Katherine S.,Kober, Brian J.,et al.
, p. 325 - 332 (2007/10/02)
Chemical and spectral properties of a series of 1-oxa-5,6-diazaspirohept-6-en-4-ones, synthesized by the oxidation of 4-alkylidene- or 4-arylidene-1-aryl-2-pyrazolin-5-ones are reported
