138907-73-0

Basic information

• Product Name: ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate
• Synonyms: ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate;Ethyl 1-(4-fluorophenyl)
• CAS NO: 138907-73-0
• Molecular Formula: C₁₂H₁₁FN₂O₂
• Molecular Weight: 234.2263432
• Mol File: 138907-73-0.mol
• Article Data: 8

Chemical Properties

• Appearance: white crystalline power
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate(138907-73-0)
• EPA Substance Registry System: ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate(138907-73-0)

Safety Data

• Hazardous Substances Data: 138907-73-0(Hazardous Substances Data)

Usage

General Description

Ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate, also known as 4-Fluoroethylphenylpyrazole, is a chemical compound with the molecular formula C12H11FN2O2. It is a pyrazole derivative and is commonly used in the field of pharmaceutical research and development. ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate has potential applications in the development of new drugs and could be used as a building block for the synthesis of various biologically active compounds. Ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate has been studied for its pharmacological properties, including its potential use as a GABA receptor modulator. Additionally, this compound may also have applications in the field of crop protection, as it has been investigated for its insecticidal and acaricidal activities.

Upstream product

• 144918-37-6 (E)-ethyl 2-cyano-3-ethoxyacrylate 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 371-14-2 4-fluorophenylhydrazine 
• 623-47-2 propynoic acid ethyl ester 
• 5352-95-4 3-(4-fluorophenyl)-3H-1,2,3-oxadiazol-1-ium-5-olate 
• 80370-42-9 ethyl 2-formyl-3-oxopropanoate 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 
• 138907-68-3 ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 
• 37622-90-5 4-ethoxycarbonylpyrazole 
• 352-34-1 4-fluoro-1-iodobenzene 

Downstream Products

• 138907-81-0 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid 
• 288249-90-1 N-(3-cyano-4-neopentyloxyphenyl)-N-[1-(4-fluorophenyl)pyrazol-4-ylcarbonyl]glycine 
• 288250-13-5 N-{3-cyano-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}-1-(4-fluorophenyl)pyrrolecarboxamide 
• 153863-44-6 [1-(4-Fluoro-phenyl)-1H-pyrazol-4-yl]-acetonitrile 
• 153863-64-0 4-(bromomethyl)-1-(4-fluorophenyl)-1H-pyrazole 
• 153863-34-4 [1-(4-fluorophenyl)-1H-pyrazol-4-yl]methanol 

Relevant articles and documents

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

nBu3P-catalyzed desulfonylative [3 + 2] cycloadditions of allylic carbonates with arylazosulfones to pyrazole derivatives

Highly efficient nBu3P-catalyzed desulfonylative [3 + 2] cycloadditions of allylic carbonates with arylazosulfones were developed for the synthesis of pyrazole derivatives. The reactions proceed smoothly under mild conditions to gene

PYRAZOLE DERIVATIVES AS P2X7 MODULATORS

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: The pyrazole derivatives of formula (I) or salts thereof modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2