13892-06-3

Basic information

• Product Name: 1,1,1-TRIMETHYL-N-(TRIPHENYLPHOSPHORANYLIDENE)SILANAMINE
• Synonyms: 1,1,1-TRIMETHYL-N-(TRIPHENYLPHOSPHORANYLIDENE)SILANAMINE;Phosphine imide, P,P,P-triphenyl-N-(trimethylsilyl)-;Silanamine, 1,1,1-trimethyl-N-(triphenylphosphoranylidene)-;Triphenyl-N-(trimethylsilyl)phosphine imide;1,1,1-trimethyl-N-(triphenylphosphoranyl-idene)si;N-(Trimethylsilyl)-P,P,P-triphenylphosphine imide;N-(Trimethylsilyl)triphenylphosphine imide;N-Trimethylsilyliminotriphenylphosphorane
• CAS NO: 13892-06-3
• Molecular Formula: C₂₁H₂₄NPSi
• Molecular Weight: 349.48
• Product Categories: Organic Building Blocks;Others;Phosphorus Compounds
• Mol File: 13892-06-3.mol

Chemical Properties

• Melting Point: 76-82 °C(lit.)
• Boiling Point: 428.9°C at 760 mmHg
• Flash Point: 213.2°C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 3.66E-07mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 1,1,1-TRIMETHYL-N-(TRIPHENYLPHOSPHORANYLIDENE)SILANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-TRIMETHYL-N-(TRIPHENYLPHOSPHORANYLIDENE)SILANAMINE(13892-06-3)
• EPA Substance Registry System: 1,1,1-TRIMETHYL-N-(TRIPHENYLPHOSPHORANYLIDENE)SILANAMINE(13892-06-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 13892-06-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,1,1-Trimethyl-N-(triphenylphosphoranylidene)silanamine is used as a synthetic reagent for the development of febrifugine derivatives. These derivatives are of interest due to their potential as effective and safer tetrahydroquinazoline-type antimalarial drugs. The compound plays a crucial role in the synthesis process, enabling the creation of new antimalarial agents with improved efficacy and reduced side effects.
Used in Organic Synthesis:
As an organic building block, 1,1,1-Trimethyl-N-(triphenylphosphoranylidene)silanamine is used in various chemical reactions to construct complex organic molecules. Its unique structure allows it to participate in a range of reactions, such as condensation, substitution, and rearrangement reactions, making it a valuable tool for the synthesis of diverse organic compounds.

InChI:InChI=1/C21H24NPSi/c1-24(2,3)22-23(19-13-7-4-8-14-19,20-15-9-5-10-16-20)21-17-11-6-12-18-21/h4-18H,1-3H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 2240-47-3 imino(triphenyl)phosphorane 
• 4648-54-8 trimethylsilylazide 
• 603-35-0 triphenylphosphine 
• 4148-01-0 N-chlorohexamethyldisilazane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 38884-84-3 C₄₂H₃₅FN₂P₃⁽¹⁺⁾*C₆H₅F₅P^(1-) 
• 33082-06-3 (triphenylphosphoranediyl)aminocyclotrithiatriazene 
• 38855-56-0 C₃₆H₃₀F₂N₂P₃⁽¹⁺⁾*F₆P^(1-) 
• 32556-31-3 C₂₀H₂₁ClNPSi 
• 4027-82-1 N-(triphenylphosphoranylidene)cyanamide 
• 58901-46-5 (4,6-dichloro-[1,3,5]triazin-2-yl)-triphenyl-λ⁵-phosphanylidene-amine 
• 35235-78-0 C₂₃H₁₈N₃O₂P 
• 116704-33-7 C₂₃H₂₂NO₃P 
• 138503-98-7 C₂₅H₂₂Cl₂NOPTe 
• 1118-02-1 trimethylsilyl isocyanate 
• 85019-55-2 N-(1-phenyl-2,2,2-trifluoroethylidene)-N'-(triphenylphosphoranediyl)urea 
• 30543-46-5 N-phenyl-N'-(trimethylsilyl)carbodiimide 

Relevant articles and documents

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Facile preparation of silyl azides with dipolar aprotic solvents

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