13893-45-3

Basic information

• Product Name: DL-Valine, ethyl ester
• CAS NO: 13893-45-3
• Molecular Formula: C7H15NO2
• Molecular Weight: 145.202
• Mol File: 13893-45-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: DL-Valine, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: DL-Valine, ethyl ester(13893-45-3)
• EPA Substance Registry System: DL-Valine, ethyl ester(13893-45-3)

Safety Data

• Hazardous Substances Data: 13893-45-3(Hazardous Substances Data)

Usage

General Description

DL-Valine, ethyl ester is a chemical compound that is the ethyl ester of DL-valine, which is an essential amino acid. It is commonly used in the food and pharmaceutical industries as a flavoring agent and a precursor for the production of various drugs and pharmaceuticals. DL-Valine, ethyl ester is also used in the synthesis of peptides and as a building block for the creation of new chemical compounds. Additionally, it has been researched for its potential use in the treatment of various medical conditions, including neurological disorders and muscle wasting diseases. As a chemical compound, DL-Valine, ethyl ester plays a crucial role in the development of new products and treatments in the fields of food science, pharmaceuticals, and medicine.

Upstream product

• 64-17-5 ethanol 
• 640-68-6 D-Val-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 17431-03-7 L-valine ethyl ester 
• 3479-71-8 Boc-D-Val-Gly-OEt 
• 143673-66-9 (R)-3-(1-methylethyl)-piperazine-2,5-one 
• 110117-71-0 (2R)-3,6-diethoxy-2-isopropyl-2,5-dihydropyrazine 
• 22838-58-0 Boc-D-Val-OH 
• 501-53-1 benzyl chloroformate 
• 174136-28-8 2-Bromo-3-((2S,5R)-3,6-diethoxy-5-isopropyl-2,5-dihydro-pyrazin-2-ylmethyl)-5-methoxy-indole-1-carboxylic acid tert-butyl ester 
• 196713-99-2 tert-butyl 2-bromo-3-(((2S,5R)-3,6-diethoxy-5-isopropyl-2,5-dihydropyrazin-2-yl)methyl)-1H-indole-1-carboxylate 
• 140170-77-0 (R)-2-[Benzyl-((R)-2-hydroxy-1-phenyl-ethyl)-amino]-3-methyl-butyric acid ethyl ester 

Downstream Products

• 5625-50-3 cyclo-(Leu-Val) 
• 4910-25-2 N-phenylsulfanylcarbonyl-DL-valine ethyl ester 
• 116890-11-0 N-[(RS)-2-methoxycarbonyl-2-(2-phenyl-acetylamino)-ethyl]-DL-valine ethyl ester 
• 106172-66-1 N-(N^α-benzyloxycarbonyl-L-histidyl)-Ξ-valine 
• 16369-05-4 valinol 
• 3350-55-8 (R)-(-)-valine ethyl ester 
• 19943-14-7 3,6-diisopropyl-piperazine-2,5-dione 
• 13474-14-1 valinamide 
• 42930-58-5 2-(2-Benzoylamino-2-methyl-propionylamino)-3-methyl-butyric acid ethyl ester 
• 4910-34-3 (+/-)-N--valin-aethylester 
• 640-68-6 D-Val-OH 
• 85847-89-8 2-Fluoro-3-methyl-butyric acid ethyl ester 
• 85847-88-7 ethyl 3-fluoro-3-methylbutanoate 
• 20201-24-5 ethyl 3-methyl-2-oxobutanoate 

Relevant articles and documents

Accessing d-Valine Synthesis by Improved Variants of Bacterial Cyclohexylamine Oxidase

Chemoenzymatic deracemization was applied to prepare d-valine from racemic valine ethyl ester or l-valine ethyl ester in high yield (up to 95 %) with excellent optical purity (>99 % ee) by employing a newly evolved cyclohexylamine oxidase (CHAO) variant Y321I/M226T exhibiting catalytic efficiency that was 30 times higher than that of the wildtype CHAO. Interestingly, CHAO and its variants showed opposite enantioselectivity for valine ethyl ester and phenylalanine ethyl ester.

Stereospecific Synthesis of 3,4-Dihydro-2 H-naphtho-1,4-oxazin-2-ones by Unification of Benzoxepine-4-carboxylates with Chiral Amino Acid Ethyl Esters

A novel and efficient stereocontrolled method has been developed for the preparation of chiral 3,4-dihydro-2H-naphtho[1,2-b][1,4]oxazin-2-ones by the reaction of benzoxepine-4-carboxylates with chiral amino acid ethyl esters for the first time. The chiral 3,4-dihydro-2H-naphtho-1,4-oxazinones have been achieved in one step by the formation of C-N, C-C, and C-O bonds.

A Strategy Towards the Stereoselective Synthesis of 5-Hydroxylysine

A stereoselective synthesis of 5-hydroxylysine is described in which the α-stereogenic centre is generated by a Schoellkopf amino acid synthesis, and the ethanolamine structure is obtained via Sharpless aminohydroxylation from an olefin moiety. The reactions and their selectivities are studied.