139016-12-9

Basic information

• Product Name: 2,3-dihydro-2-(4′-methoxyphenyl)-5-methoxybenzofuran
• Synonyms: 2,3-dihydro-2-(4′-methoxyphenyl)-5-methoxybenzofuran
• CAS NO: 139016-12-9
• Molecular Weight: 256.301
• Mol File: 139016-12-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2,3-dihydro-2-(4′-methoxyphenyl)-5-methoxybenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-2-(4′-methoxyphenyl)-5-methoxybenzofuran(139016-12-9)
• EPA Substance Registry System: 2,3-dihydro-2-(4′-methoxyphenyl)-5-methoxybenzofuran(139016-12-9)

Safety Data

• Hazardous Substances Data: 139016-12-9(Hazardous Substances Data)

Upstream product

• 637-69-4 4-Methoxystyrene 
• 1019652-04-0 2-(2-bromo-5-methoxy-phenyl)-1-(4-methoxy-phenyl)-ethanol 
• 1019652-05-1 1′-(3-methoxyphenyl)-2′-(4′′-methoxyphenyl)ethan-2′-ol 
• 935-50-2 4,4-dimethoxycyclohexa-2,5-dienone 
• 150-76-5 4-methoxy-phenol 
• 1798-09-0 m-methoxyphenylacetic acid 
• 98540-26-2 1′-(3-methoxyphenyl)-2′-(4′′-methoxyphenyl)ethan-2′-one 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 144828-84-2 N-methoxy-1′-(3-methoxyphenyl)-N-methylacetamide 
• 6689-38-9 (4-methoxyphenoxy)trimethylsilane 
• 106-51-4 p-benzoquinone 
• 464916-10-7 5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzofuran 
• 74-88-4 methyl iodide 

Downstream Products

• 1020002-96-3 (S)-5-methoxy-2-(4-methoxyphenyl)-2,3-dihydrobenzofuran 
• 19803-11-3 6-methoxy-2-(4-methoxyphenyl)benzofuran 

Relevant articles and documents

Synthesis, Characterization, and Reaction of a Both Inter- and Intramolecularly Coordinated Pseudocyclic Iodosylbenzene–Trifluoroacetic Acid Complexes

An ortho-substituted ether-oxygen-coordinated pseudocyclic iodosylbenzene-trifluoroacetic acid (pcISB-TFA) complex was synthesized and characterized by X-ray crystallographic analysis. TFA suppresses the disproportionation by both coordination of the oxygen atom to the iodine(III) center through secondary bonding and by hydrogen bonding to the oxygen anion. This bench-stable reagent is highly soluble in common organic solvents and reacts with various organic substrates under mild reaction conditions to give the corresponding products in good yields.

Synthesis of Functionalized Indolines and Dihydrobenzofurans by Iron and Copper Catalyzed Aryl C-N and C-O Bond Formation

A simple and effective one-pot, two-step intramolecular aryl C-N and C-O bond forming process for the preparation of a wide range of benzo-fused heterocyclic scaffolds using iron and copper catalysis is described. Activated aryl rings were subjected to a highly regioselective, iron(III) triflimide-catalyzed iodination, followed by a copper(I)-catalyzed intramolecular N-or O-arylation step leading to indolines, dihydrobenzofurans, and six-membered analogues. The general applicability and functional group tolerance of this method were exemplified by the total synthesis of the neolignan natural product, (+)-obtusafuran. DFT calculations using Fukui functions were also performed, providing a molecular orbital rationale for the highly regioselective arene iodination process.

A process for the preparation of benzofuran compounds (by machine translation)

The present invention provides a method for the preparation of benzofuran compounds, comprises: under the nitrogen atmosphere, sulfate and organic solvent in the presence of, the three a base silicon group protection of the methoxyphenol compound reaction