139047-55-5 Usage
Uses
2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects.
Biological Activity
Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM).
Check Digit Verification of cas no
The CAS Registry Mumber 139047-55-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,0,4 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 139047-55:
(8*1)+(7*3)+(6*9)+(5*0)+(4*4)+(3*7)+(2*5)+(1*5)=135
135 % 10 = 5
So 139047-55-5 is a valid CAS Registry Number.
139047-55-5Relevant articles and documents
Studies on Quinazolines. 5. 2,3-Dihydroimidazoquinazoline Derivatives: A Novel Class of Potent and Selective α1-Adrenoceptor Antagonists and Antihypertensive Agents
Chern, Ji-Wang,Tao, Pao-Luh,Yen, Mao-Hsiung,Lu, Guan-Yu,Shiau, Chia-Yang,et al.
, p. 2196 - 2207 (2007/10/02)
A series of 2-- and 2--2,3-dihydroimidazoquinazolin-5(6H)-ones or -5(6H)-thiones, and 3--2,3-dihydroimidazoquinazol
