139047-57-7

Upstream product

• 28144-70-9 anthranilic acid amide 
• 13906-09-7 2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 54855-81-1 2-methylthioquinazolin-4(3H)-one 
• 58803-74-0 4-chloro-2-(methylthio)quinazoline 
• 48141-61-3 2,4-bis(methylthio)quinazoline 
• 139047-56-6 4-allylamino-2-methylthioquinazolin 

Downstream Products

• 139047-58-8 3-<(4-phenylpiperazine-1-yl)methyl>-5-(methylthio)-2,3-dihydroimidazo<1,2-c>quinazoline 
• 149847-79-0 DL 017 
• 149847-84-7 3-<<4-(2-chlorophenyl)piperazine-1-yl>methyl>-5-methoxy-2,3-dihydroimidazo<1,2-c>quinazoline 
• 149847-88-1 3-<<4-(2-chlorophenyl)piperazin-1-yl>methyl>-2,3-dihydroimidazo<1,2-c>quinazolin-5(6H)-one 
• 149847-74-5 3-<(4-phenylpiperazine-1-yl)methyl>-5-methoxy-2,3-dihydroimidazo<1,2-c>quinazoline 
• 139047-59-9 3-(4-Phenyl-1-piperazinyl)-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one 
• 212143-80-1 2-Bromo-3-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-6H-imidazo[1,2-c]quinazolin-5-one 
• 212143-84-5 3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-6H-imidazo[1,2-c]quinazolin-5-one 
• 212143-81-2 2-Bromo-3-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-6H-imidazo[1,2-c]quinazolin-5-one 
• 212143-85-6 3-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-6H-imidazo[1,2-c]quinazolin-5-one 
• 149847-81-4 3-<<4-(3-methoxyphenyl)piperazine-1-yl>methyl>-5-(methylthio)-2,3-dihydroimidazo<1,2-c>quinazoline 
• 149847-80-3 3-<<4-(2-chlorophenyl)piperazine-1-yl>methyl>-5-(methylthio)-2,3-dihydroimidazo<1,2-c>quinazoline 
• 149847-82-5 3-<<4-(4-methoxyphenyl)piperazine-1-yl>methyl>-5-(methylthio)-2,3-dihydroimidazo<1,2-c>quinazoline 

Relevant academic research and scientific papers

Kilogram-scale synthesis of a highly selective α1-adrenoceptor antagonist (DL-028A)

This work presents an improved eight-step process, leading to kilogram quantities of high-quality DL-028A, an antihypertensive agent. The improvements include reducing the levels of toxic reagents and the removal of dangerous processes and waste gas treatment. Moreover, specification and impurity profiles were determined.

3-SUBSTITUTED METHYL-2,3-DIHYDROIMIDAZO[1,2-C] QUINAZOLINE DERIVATIVES, THE PREPARATION AND USE THEREOF

The present invention provides a novel series of 3-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazoline compounds. These compounds are found useful as an active ingredient for the treatment of hypertension and dysuria.

Studies on Quinazolines. 5. 2,3-Dihydroimidazoquinazoline Derivatives: A Novel Class of Potent and Selective α1-Adrenoceptor Antagonists and Antihypertensive Agents

A series of 2-- and 2--2,3-dihydroimidazoquinazolin-5(6H)-ones or -5(6H)-thiones, and 3--2,3-dihydroimidazoquinazol