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CAS

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1390635-89-8

{1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1390635-89-8 Structure

  • Basic information

    1. Product Name: {1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate
    2. Synonyms: {1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate
    3. CAS NO:1390635-89-8
    4. Molecular Formula:
    5. Molecular Weight: 495.561
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1390635-89-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: {1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: {1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate(1390635-89-8)
    11. EPA Substance Registry System: {1-[2-(4-cyanophenyl)-2-oxoethyl]-1H-1,2,3-triazol-4-yl}methyl 3-(10H-phenothiazin-10-yl)propanoate(1390635-89-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1390635-89-8(Hazardous Substances Data)

1390635-89-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1390635-89-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,0,6,3 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1390635-89:
(9*1)+(8*3)+(7*9)+(6*0)+(5*6)+(4*3)+(3*5)+(2*8)+(1*9)=178
178 % 10 = 8
So 1390635-89-8 is a valid CAS Registry Number.

1390635-89-8Downstream Products

1390635-89-8Relevant articles and documents

New farnesyltransferase inhibitors in the phenothiazine series

Belei, Dalila,Dumea, Carmen,Samson, Alexandrina,Farce, Amaury,Dubois, Joelle,Bicu, Elena,Ghinet, Alina

, p. 4517 - 4522 (2012/08/07)

The biological screening of the chemical library of our Organic Chemistry Department, carried out on an automated fluorescence-based FTase assay, allowed us to discover that a phenothiazine derivative (1d) was an inhibitor of farnesyltransferase. Three new series of human farnesyltransferase inhibitors, based on a phenothiazine scaffold, were synthesized with protein farnesyltransferase inhibition potencies in the low micromolar range. Ester derivative 9d was the most active compound in these series. Four synthesized compounds were evaluated for their antiproliferative activity on a NCI-60 cancer cell line panel. The modest results obtained in this preliminary investigation showed that mixing the phenothiazine and the 1,2,3-triazole motif in the structure of a single compound can lead to new scaffolds in the field of farnesyltransferase inhibitors.

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