13908-32-2

Basic information

• Product Name: N-(2-CHLOROETHYL)-N'-(4-FLUOROPHENYL)UREA
• Synonyms: N-(2-CHLOROETHYL)-N'-(4-FLUOROPHENYL)UREA;1-(2-Chloroethyl)-1-(4-fluorophenyl)urea
• CAS NO: 13908-32-2
• Molecular Formula: C₉H₁₀ClFN₂O
• Molecular Weight: 216.64
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 13908-32-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 132°C
• Boiling Point: 295.7°Cat760mmHg
• Flash Point: 132.6°C
• Appearance: /
• Density: 1.325g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2-CHLOROETHYL)-N'-(4-FLUOROPHENYL)UREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-CHLOROETHYL)-N'-(4-FLUOROPHENYL)UREA(13908-32-2)
• EPA Substance Registry System: N-(2-CHLOROETHYL)-N'-(4-FLUOROPHENYL)UREA(13908-32-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 13908-32-2(Hazardous Substances Data)

Usage

General Description

N-(2-chloroethyl)-N'-(4-fluorophenyl)urea is a chemical compound with the molecular formula C9H10ClFN2O. It is a urea derivative that is used as a building block in organic synthesis and drug development. It is commonly used in the pharmaceutical industry for the synthesis of various drugs and compounds. N-(2-chloroethyl)-N'-(4-fluorophenyl)urea has potential applications in the treatment of various diseases and conditions, and its unique chemical structure makes it a valuable tool in medicinal chemistry and drug discovery. It is important to handle this chemical with care and follow appropriate safety protocols when working with it in a laboratory setting.

Upstream product

• 1195-45-5 para-fluorophenyl isocyanate 
• 689-98-5 chloroethylamine 
• 870-24-6 2-chloroethanamine hydrochloride 
• 1943-83-5 2-chloroethyl isothiocyanate 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 1596360-60-9 methyl 6-[[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxylate 
• 1596360-40-5 N-[(1S)-5-amino-1-cyano-pentyl]-6-[[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carboxamide 
• 1596360-83-6 9H-fluoren-9-ylmethyl N-[(5S)-5-cyano-5-[[6-[[3-(4-fluorophenyl)-2-oxo-imidazolidin-1-yl]methyl]-7-methyl-pyrrolo[2,3-d]pyrimidine-2-carbonyl]amino]pentyl]carbamate 
• 13909-17-6 C₉H₉ClFN₃O₂ 
• 53159-75-4 1-(4-fluorophenyl)-2-oxo-tetrahydroimidazole 

Relevant articles and documents

Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin

In the development of plasmin inhibitors, a novel chemotype, pyrrolopyrimidine scaffold possessing two motifs, a hydantoin-containing P4 moiety and a warhead-containing P1 moiety, is uncovered. A unique feature of the new line of the plasmin inhibitors is

New substituted 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with α2-adrenoceptor antagonist activity

The emergence of a novel theory concerning the role of noradrenaline in the progression and the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases has provided a new impetus toward the discovery of novel compounds acting at α2-adrenoceptors. A series of substituted 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl derivatives bearing an amide, urea, or imidazolidinone moiety was studied. Some members of this series of compounds proved to be potent α2-adrenoceptor antagonists with good selectivity versus α1-adrenergic and D2-dopamine receptors. Particular emphasis is given to compound 33g which displays potent α2-adrenoceptor binding affinity in vitro and central effects in vivo following oral administration.