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(2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 139163-87-4 Structure
  • Basic information

    1. Product Name: (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate
    2. Synonyms: (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate
    3. CAS NO:139163-87-4
    4. Molecular Formula:
    5. Molecular Weight: 209.245
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 139163-87-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate(139163-87-4)
    11. EPA Substance Registry System: (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate(139163-87-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 139163-87-4(Hazardous Substances Data)

139163-87-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 139163-87-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,1,6 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 139163-87:
(8*1)+(7*3)+(6*9)+(5*1)+(4*6)+(3*3)+(2*8)+(1*7)=144
144 % 10 = 4
So 139163-87-4 is a valid CAS Registry Number.

139163-87-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,2R)-3-amino-2-hydroxy-4-phenylbutyric acid methyl ester

1.2 Other means of identification

Product number -
Other names (2R,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139163-87-4 SDS

139163-87-4Relevant articles and documents

Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1

Kakizawa, Taeko,Hidaka, Koushi,Hamada, Daisuke,Yamaguchi, Ryoji,Uemura, Tsuyoshi,Kitamura, Hitomi,Tagad, Harichandra D.,Hamada, Takashi,Ziora, Zyta,Hamada, Yoshio,Kimura, Tooru,Kiso, Yoshiaki

scheme or table, p. 257 - 262 (2011/03/18)

β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is known to be involved in the production of amyloid β-peptide in Alzheimer's disease and is a major target for current drug design. We previously reported substrate-based peptidomimetics, KMI-com

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE

-

Page 37-38, (2008/06/13)

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

Application of the asymmetric aminohydroxylation reaction for the syntheses of HIV-protease inhibitor, hydroxyethylene dipeptide isostere and γ-amino acid derivative

Kondekar, Nagendra B.,Kandula, Subba Rao V.,Kumar, Pradeep

, p. 5477 - 5479 (2007/10/03)

An enantioselective synthesis of lactone 1, a precursor to the (2R,4S,5S) hydroxyethylene dipeptide isostere and amino acid AHPPA 2 has been accomplished from the common intermediate 5 employing Sharpless asymmetric aminohydroxylation as the key step.

Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3′ residue

Mak, Chi Ching,Le, Van-Duc,Lin, Ying-Chuan,Elder, John H,Wong, Chi-Huey

, p. 219 - 222 (2007/10/03)

A series of norstatine-based HIV/FIV protease inhibitors incorporating a 15-membered macrocycle as a mimic of the tripeptide (Ala-Val-Phe), a motif with a small P3′ residue effective against the FIV protease and the drug-resistant HIV proteases, has been

Asymmetric synthesis of 3-amino-2-hydroxy-4-phenylbutanoate

Ha, Hyun-Joon,Ahn, Young-Gil,Lee, Gwan Sun

, p. 2327 - 2336 (2007/10/03)

Asymmetric synthesis of 3-amino-2-hydroxy-4-phenylbutanoate, a key component of the natural product bestatin and HIV protease inhibitors of KNI- 272 and R-87366, has been achieved from the stereoselective aldimine coupling reaction between 3-phenyl-2-aminopropanenitrile and (Z)-α-methoxy trimethylsilyl ketene acetal in the presence of Lewis acids.

Development of selective tight-binding inhibitors of leukotriene A4 hydrolase

Yuan,Munoz,Wong,Haeggstrom,Wetterholm,Samuelsson

, p. 211 - 220 (2007/10/02)

Leukotriene A4 hydrolase is a zinc-containing enzyme which exhibits both epoxide hydrolase and aminopeptidase activities. Since the enzyme product leukotriene B4 is an inflammatory mediator, it is of interest to develop selective inh

A Practical Synthesis of threo-3-Amino-2-hydroxycarboxylic Acids

Matsuda, Fuyuhiko,Mtsumoto, Teruyo,Ohsaki, Masako,Ito, Yoshio,Terashima, Shiro

, p. 360 - 365 (2007/10/02)

An expeditious synthesis of (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid (2) and (2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid (4), the key components of the renin inhibitor (1) and bestatin (3), respectively, have been accomplished by featuring hi

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