139165-56-3

Upstream product

• 122-78-1 phenylacetaldehyde 
• 1560-06-1 1-phenyl-2-butene 
• 1190977-30-0 (2R,3R)-1-phenyl-2,3-butanediol 2-O-β-D-apiofuranosyl-(1->6)-β-D-glucopyranoside 
• 1190977-18-4 (2R,3R)-1-phenyl-2,3-butanediol 2-O-β-D-glucopyranoside 
• 169302-20-9 (2R,3R)-3,4-epoxy-1-phenyl-2-butanol 3,5-dinitrobenzoate 
• 169302-18-5 (2S,3R)-3,4-epoxy-1-phenyl-2-butanol 
• 6052-66-0 1-phenyl-3-buten-2-ol 
• 114-76-1 sodium phenylphyruvate 
• 169302-22-1 (2R,3R)-3,4-epoxy-1-phenyl-2-butanol 

Downstream Products

• 1450899-55-4 (5R,6R)-5-benzyl-2,2,3,3,6,8,8,9,9-nonamethyl-4,7-dioxa-3,8-disiladecane 

Relevant academic research and scientific papers

Asymmetric acyloin condensation catalyzed by phenylpyruvate decarboxylase

Cells obtained from growth of Achromobacter eurydice, Pseudomonas aromatica and Pseudomonas putida on L-phenylalanine containing medium catalyzed the enzymatic acyloin condensation of phenylpyruvic acid 1 and acetaldehyde 2 by phenylpyruvate decarboxylase

Total synthesis of nhatrangin a

A concise and stereoselective approach for the synthesis of key intermediates for aplysiatoxins, oscillatoxins, and nhatrangins and their utility for the total synthesis of nhatrangin A has been demonstrated. The advanced intermediates aromatic aldehyde 11 and dihydroxy acid 12 were synthesized in eight steps (44% overall yield) and three steps (55% overall yield), respectively. An asymmetric Michael addition, CBS reduction, and proline-catalyzed crossed-aldol reactions were utilized as key steps for the generation of all the chirality of main chain hydroxyaldehyde, while the appended side-chain-protected 3,4-dihydroxypentanoic acid was achieved in a shortest route, using Sharpless dihydroxylation, diol protection, and RuO 4-catalyzed aromatic over-oxidation reactions. Synthesis of nhatrangin A was accomplished by coupling of dihydroxy acid 12 with β-hydroxyallyl ester (obtained from 11) under Yamaguchi reaction conditions followed by a one-pot deprotection of all protecting groups.

Medicinal flowers. XXX. Eight new glycosides, everlastosides F - M, from the flowers of Helichrysum arenarium

Eight new glycosides, everlastosides F (1), G (2), H (3), I (4), J (5), K (6), L (7), and M (8), were isolated from the methanolic extract of the flowers of Helichrysum arenarium. Their structures were elucidated on the basis of chemical and physicochemic

Synthesis of All Four Possible Stereoisomers of 1-Phenyl-2,3-butanediol and Both Enantiomers of 3-Hydroxy-4-phenyl-2-butanone to Determine the Absolute Configuration of the Natural Constituents

Enantioselective syntheses of all the possible stereoisomers of 1-phenyl-2,3-butanediol (erythro isomer 1 and threo isomer 2) and of 3-hydroxy-4-phenyl-2-butanone 3, the odor components of wisteria flowers, was accomplished via Sharpless asymmetric epoxyd