139166-79-3Relevant articles and documents
Synthesis of a novel ester analog of nucleic acids bearing a serine backbone
Murata, Asako,Wada, Takeshi
, p. 2933 - 2936 (2006)
A novel analog of nucleic acids bearing an optically active serine ester backbone, serine-based nucleobase-linked polyester (SNE), was synthesized. Monomers containing a thymine base were synthesized from l- and d-serines. Furthermore, reaction conditions
Acyclic nucleotide analogues on the basis of phosphonic acids
Efimtseva,Mikhailov,Fomicheva,Meshkov,Rodionov,Khomutov,De Clercq
, p. 12 - 16 (2007/10/03)
The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acids was described. A rigid structural element, an amide, or a double bond, was characteristic of the compounds synthesized. The antiviral and cytotoxic activities of these compo
New approach to solid phase synthesis of polyamide nucleic acids analogues (PNA) and PNA-DNA conjugates
Stetsenko, Dmitry A.,Lubyako, Elena N.,Potapov, Viktor K.,Azhikina, Tatyana L.,Sverdlov, Evgeny D.
, p. 3571 - 3574 (2007/10/03)
New version of sequential DNA and polyamide solid phase synthesis is applied to the preparation of PNA and PNA-DNA conjugates bearing free 3'-end. N-Mmt protected uracil and thymine PNA monomers are obtained in high yields. Novel support derived from TSK
