1391870-70-4Relevant articles and documents
Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors
Mangin, Floriane,Dilly, Sebastien,Joly, Benoit,Scuvee-Moreau, Jacqueline,Evans, Jon,Setola, Vincent,Roth, Bryan L.,Liegeois, Jean-Francois
, p. 4550 - 4554 (2012/08/08)
The selectivity for 5-HT1A versus D4 receptors is significantly increased when the basic side chain of WAY-100635 is replaced by a 4-phenylpiperazine (3e) or a 4-phenyl-1,2,3,6-tetrahydropyridine moiety (3i). The 4-phenyl-1,2,3,6-tet