1391978-87-2

Upstream product

• 609-67-6 2-Iodobenzoyl chloride 
• 1391978-99-6 2-((2-azidoethyl)(4-methoxybenzyl)amino)-4,4-dimethoxyisoquinoline-1,3(2H,4H)-dione 
• 1391978-98-5 2'-((2-azidoethyl)(4-methoxybenzyl)amino)-1'H-spiro[[1,3]dithiane-2,4'-isoquinoline]-1',3'(2'H)-dione 
• 1391978-85-0 2-((2-azidoethyl)(4-methoxybenzyl)amino)isoquinoline-1,3(2H,4H)-dione 
• 1391978-96-3 N'-(2-azidoethyl)-2-iodo-N'-(4-methoxybenzyl)benzohydrazide 
• 1391978-83-8 1-(2-azidoethyl)-1-[(4-methoxyphenyl)methyl]hydrazine 

Relevant academic research and scientific papers

Synthesis of 1,2,4-triazines and the triazinoisoquinolinedione DEF ring system of noelaquinone

The intramolecular Staudinger-aza-Wittig reaction is used for a general synthesis of 1,2,5,6-tetrahydro-1,2,4-triazines, a structural motif reported for the natural product noelaquinone. The DEF moiety of noelaquinone was obtained in 13 steps and 2% overall yield, and the structure of the synthetic product was confirmed by X-ray analysis.