1392141-34-2Relevant academic research and scientific papers
Rh-Catalyzed [5+1] and [4+1] cycloaddition reactions of 1,4-enyne esters with co: A shortcut to functionalized resorcinols and cyclopentenones
Fukuyama, Takahide,Ohta, Yuko,Brancour, Celia,Miyagawa, Kazusa,Ryu, Ilhyong,Dhimane, Anne-Lise,Fensterbank, Louis,Malacria, Max
, p. 7243 - 7247 (2012/07/03)
We have developed novel Rh-catalyzed [n+1]-type cycloadditions of 1,4-enyne esters, which involve an acyloxy migration as a key step. The efficient preparation of functionalized resorcinols, including biaryl derivatives, from readily available 1,4-enyne esters and CO was achieved by Rh-catalyzed [5+1] cycloaddition accompanied by 1,2-acyloxy migration. When enyne esters had an internal alkyne moiety, the reaction proceeded by a [4+1]-type cycloaddition involving 1,3-acyloxy migration, leading to cyclopentenones.
