1392196-84-7Relevant academic research and scientific papers
Method and compositions for targeted drug delivery to the lower GI tract
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, (2016/09/13)
A composition and method for targeted delivery of substances to the lower GI tract comprises a base or scaffold carrier to which a drug or prodrug is fixed or covalently attached. Compound, when taken orally travels through the GI tract of a patient to th
Design, synthesis, and testing of a molecular truck for colonic delivery of 5-aminosalicylic acid
Navath, Suryakiran,Rao, Venkataramanarao,Woodford, Rita-Marie T.,Midura-Kiela, Monica T.,Ahad, Ali M.,Alleti, Ramesh,Kiela, Pawel R.,Mash, Eugene A.
, p. 710 - 714 (2012/11/07)
A molecular scaffold bearing eight terminal alkyne groups was synthesized from sucrose. Eight copies of an azide-terminated, azo-linked precursor to 5-aminosalicylic acid were attached to the scaffold via copper(I)-catalyzed azide-alkyne cycloaddition. Th
