139223-54-4

Basic information

• Product Name: (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate
• Synonyms: (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate
• CAS NO: 139223-54-4
• Molecular Weight: 367.51
• Mol File: 139223-54-4.mol

Chemical Properties

• CAS DataBase Reference: (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate(139223-54-4)
• EPA Substance Registry System: (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate(139223-54-4)

Safety Data

• Hazardous Substances Data: 139223-54-4(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 3282-30-2 pivaloyl chloride 
• 144434-12-8 (R)-(+)-o-(1-pivaloylaminoethyl)thiophenol 
• 130973-54-5 (R)-(-)-o-(1-pivaloylaminoethyl)benzene sulfinic acid 
• 91797-84-1 (R)-(+)-N-(1-phenylethyl)-2,2-dimethylpropanamide 
• 540-88-5 acetic acid tert-butyl ester 
• 139343-81-0 (S_(S)R)-(+)-3-methyl-2-pivaloyl-2,3-dihydroisothiazole 1-oxide 

Downstream Products

• 144434-08-2 (2S,3S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-4,4-dimethyl-pentanoic acid tert-butyl ester 
• 144434-12-8 (R)-(+)-o-(1-pivaloylaminoethyl)thiophenol 
• 139223-51-1 N-{(R)-1-[2-((S)-Methanesulfinyl)-phenyl]-ethyl}-2,2-dimethyl-propionamide 
• 72656-48-5 tert-butyl (R)-3-hydroxy-3-phenylpropanoate 
• 130973-54-5 (R)-(-)-o-(1-pivaloylaminoethyl)benzene sulfinic acid 
• 144434-07-1 (2S,3S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-3-(2-nitro-phenyl)-propionic acid tert-butyl ester 
• 144434-05-9 (S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-3-(2-methoxy-phenyl)-propionic acid tert-butyl ester 
• 144434-04-8 (2S,3S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-3-(3-methoxy-phenyl)-propionic acid tert-butyl ester 
• 144434-09-3 (S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-4-methyl-pentanoic acid tert-butyl ester 
• 119638-95-8 (R)-tert-butyl 3-hydroxy-4-methylpentanoate 
• 154728-64-0 (S)-tert-butyl 3-hydroxy-4-methylpentanoate 
• 144434-10-6 (S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-butyric acid tert-butyl ester 
• 144434-03-7 (2S,3S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-3-(4-methoxy-phenyl)-propionic acid tert-butyl ester 
• 139223-55-5 (2S,3S)-2-{(S)-2-[(R)-1-(2,2-Dimethyl-propionylamino)-ethyl]-benzenesulfinyl}-3-hydroxy-3-phenyl-propionic acid tert-butyl ester 

Relevant articles and documents

Recoverable Chiral Sulfoxides for Asymmetric Synthesis: Preparation, Regeneration and Application to the Asymmetric Aldol Reaction

The synthesis of a novel source of chiral sulfoxide and its application to the control of asymmetric aldol reactions is described.The sulfoxide precursor S(S)R-(+)-cis-4 may be recycled and thus affords a considerable advantage over currently a

Dependence of Ring Closure Stereoselectivity on the Nature of the Leaving Group: Application to the Synthesis of a New Class of Chiral Sulfoxide for the Control of Asymmetric Aldol Reactions

Enantiomerically pure cyclic sulfinamide (S(S)R)-(+)-1 , which has application to the control of asymmetric aldol reactions via a derived sulfoxide, has been prepared in diastereoisomerically pure form from the sulfinic acid (R)-(-)-5 using thionyl chloride-4-dimethylaminopyridine (DMAP); replacement of DMAP with pyridine or triethylamine gave both diastereoisomers of 1 in low diastereoisomeric excess.